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420123 JNK Inhibitor II, Negative Control - CAS 54642-23-8 - Calbiochem

Overview

Key Spec Table

CAS #Empirical Formula
54642-23-8C₁₅H₁₀N₂O

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420123-1MG
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      Description
      OverviewA useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119). Inhibits JNK2 and JNK3 only at much higher concentrations (IC50 = 18 µM and 24 µM, respectively) compared to SP600125 (IC50 = 40 nM and 90 nM, respectively).
      Catalogue Number420123
      Brand Family Calbiochem®
      SynonymsN¹-Methyl-1,9-pyrazoloanthrone
      References
      ReferencesShin, M., and Boyd, Y.D. 2002. Biochim. Biophys. Acta 1589, 311.
      Bennett, B.L., et al. 2001. Proc. Natl. Acad. Sci. USA 98, 13681.
      Product Information
      CAS number54642-23-8
      ATP CompetitiveY
      FormYellow solid
      Hill FormulaC₁₅H₁₀N₂O
      Chemical formulaC₁₅H₁₀N₂O
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetA useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119)
      Primary Target IC<sub>50</sub>18 µM and 24 µM against JNK2 and JNK3, respectively
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableY
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      420123-1MG 04055977188035