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GF424 HumanKine® IL-23, Human Recombinant Xeno-Free

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: Q5VWK5
GF424
10 µg  
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      Overview

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      Bulk Size Quantities of HumanKine Growth Factors are Available.
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      Key Spec Table

      SourcePurity
      HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.Product is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE.
      Description
      Catalogue NumberGF424
      Trade Name
      • HumanKine®
      DescriptionHumanKine® IL-23, Human Recombinant Xeno-Free
      Alternate Names
      • Interleukin-23
      • IL23
      Background InformationInterleukin-23 (IL-23) is a heterodimer, the combination of IL-23-specific subunit p19 and IL-12 subunit p40 comprise the biologically active protein. Like IL-12, IL-23 has been shown to activate the transcription factor STAT4 (signal transducer and activator of transcription-4). Unlike IL-12, IL-23 also seems to play a role in the signaling of memory T cells. IL-23, in conjunction with IL-17, is important in controlling the bacterial growth and inflammation response in an organism with tuberculosis. It has the ability to induce Th17 activation and stimulate inflammation in many tissue types including periodontal lesions.
      Product Information
      Formulation
      PresentationProduct is presented in PBS and filtered through a 0.2 micron filter before lyophilization.
      Quality LevelMQ300
      Biological Information
      PurityProduct is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE.
      SourceHumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.
      UniProt Number
      Product Usage Statements
      Quality AssuranceBioactivity assay: Determined by the dose-dependent secretion of h-IFN-gamma from human PBMC. ED50 is typically 2-20 ng/ml.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C for up to 4 months from date of receipt. Further dilutions should be made into appropriate buffer or medium to which protein has been added.
      Packaging Information
      Material Size10 µg
      Global Trade Item Number
      Catalogue Number GTIN
      GF424 04053252905919