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SCR600 Human Oligodendrocyte Differentiation Kit

The Human Oligodendrocyte Differentiation Kit contains Human Oligodendrocyte Progenitor Cells (OPCs) along with optimized media for their expansion & spontaneous differentiation into mature oligodendrocytes.

Human Oligodendrocyte Differentiation Kit MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Stem Cell Culture
SCR600
1 kit  
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      Overview

      Replacement Information

      Key Spec Table

      Key Applications
      Cult
      Description
      Catalogue NumberSCR600
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionHuman Oligodendrocyte Differentiation Kit
      OverviewEMD Millipore’s Human Oligodendrocyte Differentiation Kit contains Human Oligodendrocyte Progenitor Cells (OPCs) along with optimized media for their expansion and spontaneous differentiation into mature oligodendrocytes. Human Oligodendrocyte Progenitor Cells (OPCs) are derived from NIH approved H9 human embryonic stem cells (hESCs). These hESC-derived OPCs proliferate as an adherent cell monolayer and greater than 70% express the appropriate early-to-intermediate oligodendrocyte markers, including O4, NG2, Olig2, Sox10 and GalC. Upon growth factor withdrawal, Human OPCs spontaneously differentiate into mature oligodendrocytes expressing terminally differentiated markers including proteolipid protein (PLP), myelin basic protein (MBP), and myelin oligodendrocyte glycoprotein (MOG). Spontaneous differentiation leads to approximately 30% of the cells expressing PLP, MBP and MOG while the remaining 70% express mostly neuronal markers, MAP2 and beta III-tubulin with very little to no astrocytes (<5% GFAP-positive cells) observed. Human OPCs can be used for a variety of research applications including studies of neurotoxicity, co-culture applications and screening for molecules that induce or inhibit preferential differentiation to mature oligodendrocytes.
      References
      Product Information
      Components
      • Human Oligodendrocyte Progenitors (OPCs), 500,000 viable cells: (Cat. No. CS204496)
      • Human OPC Expansion Media Kit, 100 mLs: (Cat. No. SCM107)
      • Human OPC Spontaneous Differentiation Media Kit, 100 mLs: (Cat. No. SCM106)
      Quality LevelMQ100
      Applications
      ApplicationThe Human Oligodendrocyte Differentiation Kit contains Human Oligodendrocyte Progenitor Cells (OPCs) along with optimized media for their expansion & spontaneous differentiation into mature oligodendrocytes.
      Key Applications
      • Stem Cell Culture
      Biological Information
      Stem Cell Type
      • Neural Stem Cells
      Cell Line Type
      • Neural Stem Cells
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceSterility testing: Negative for bacterial and fungal growth
      pH: 7.4 +/- 0.4
      Osmolality: 290 +/- 20mOsm
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsPlease see manual for recommended storage conditions for individual components
      Packaging Information
      Material Size1 kit
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      SCR600 04053252017261

      Documentation

      Brochure

      Title
      Human Stem Cell Systems
      Neuroscience Product Selection Guide
      Simplifying the iPSC Workflow

      Technical Info

      Title
      Derivation of oligodendrocyte progenitor cells from a human neural stem cell line

      Data Sheet

      Title
      Reprogramming Cell Fate and Function Novel Strategies for iPSC Generation, Characterization, and Differentiation

      Posters

      Title
      A unifying neural differentiation platform to direct lineage-specific neurons and glial cells from human pluripotent stem cells

      User Guides

      Title
      Human Oligodendrocyte Differentiation Kit

      Newsletters / Publications

      Title
      Cellutions - The newsletter for Cell Biology Researchers Volume 3: 2011

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      Categories

      Life Science Research > Cell Culture and Systems > Cell Lines > Stem Cell Lines