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AG253 Heme Oxygenase 1, control peptide for AB1284

AG253
100 µg  
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      Overview

      Replacement Information
      Description
      Catalogue NumberAG253
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionHeme Oxygenase 1, control peptide for AB1284
      OverviewSynthetic peptide corresponding to amino acid residues [12-25]+Cys-NH2 of human heme oxygenase-1. Sequence: H-D-L-S-E-A-L-K-E-A-T-K-E-V-H-C-NH2. This sequence is totally conserved in HO-1 from pig, rat and mouse.

      MOLECULAR WEIGHT:

      1671.9
      References
      Product Information
      PresentationWhite lyophilized powder. Soluble in water.
      Quality LevelMQ100
      Applications
      Key Applications
      • Peptide Inhibition Assay
      Application NotesAntibody blocking (AB1284)

      Optimal working dilution must be determined by the end user.
      Biological Information
      Purity88% by HPLC
      Entrez Gene Number
      Entrez Gene SummaryHeme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.
      Gene Symbol
      • HMOX1
      • HO
      • HO-1
      • OTTHUMP00000028925
      • bK286B10
      • HO1
      • EC 1.14.99.3
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P09601 # Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed.
      SIZE: 288 amino acids; 32819 Da
      SUBCELLULAR LOCATION: Microsome.
      SIMILARITY: SwissProt: P09601 ## Belongs to the heme oxygenase family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsLong term storage at -20°C in a sealed container with desiccant.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      AG253 04053252279089

      Documentation

      Heme Oxygenase 1, control peptide for AB1284 SDS

      Title

      Safety Data Sheet (SDS) 

      Heme Oxygenase 1, control peptide for AB1284 Certificates of Analysis

      TitleLot Number
      HUMAN HEME OXYGENASE-1 CONTROL PEPTIDE - 2049246 2049246
      HUMAN HEME OXYGENASE-1 CONTROL PEPTIDE - 2326393 2326393

      References

      Reference overviewPub Med ID
      Human heme oxygenase cDNA and induction of its mRNA by hemin.
      Yoshida, T, et al.
      Eur. J. Biochem., 171: 457-61 (1988)  1988

      Show Abstract
      3345742 3345742