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203820
Sigma-AldrichGuanosine 3ʹ,5ʹ-cyclic Monophosphate, 8-Bromo-, Sodium Salt - CAS 51116-01-9 - Calbiochem
Cell-permeable cGMP analog that is more resistant to phosphodiesterases than cGMP.
More>>Cell-permeable cGMP analog that is more resistant to phosphodiesterases than cGMP. Less<<
MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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Description
Overview
Cell-permeable cGMP analog that is more resistant to phosphodiesterases than cGMP. Preferentially activates protein kinase G. Inhibits thrombin-stimulated arachidonic acid release in human platelets.
Catalogue Number
203820
Brand Family
Calbiochem®
Synonyms
8-Bromo-cGMP, Br-cGMP, Na
References
References
Kwak, B.R., and Jongsma, H.J. 1996. Mol. Cell. Biochem. 157, 93. Perreault, T., and DeMarte, J. 1993. Am. J. Physiol. 264, H302. Ruth, P., et al. 1991. Eur. J. Biochem.202, 1339. Schwarzschild, M.A., and Zigmond, R.E. 1991. J. Neurochem.56, 400.
Guanosine 3ʹ,5ʹ-cyclic Monophosphate, 8-Bromo-, Sodium Salt - CAS 51116-01-9 - Calbiochem Certificates of Analysis
Title
Lot Number
203820
References
Reference overview
Kwak, B.R., and Jongsma, H.J. 1996. Mol. Cell. Biochem. 157, 93. Perreault, T., and DeMarte, J. 1993. Am. J. Physiol. 264, H302. Ruth, P., et al. 1991. Eur. J. Biochem.202, 1339. Schwarzschild, M.A., and Zigmond, R.E. 1991. J. Neurochem.56, 400.
Citations
Title
Bing Zhu, Samuel Strada and Troy Stevens. (2005) Cyclic GMP-specific phosphodiesterase 5 regulates growth and apoptosis in pulmonary endothelial cells. American Journal of Physiology Lung Cellular and Molecular Physiology289, L196-L206.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
22-May-2008 RFH
Synonyms
8-Bromo-cGMP, Br-cGMP, Na
Description
Cell-permeable cGMP analog that is more resistant to phosphodiesterases than cGMP. Preferentially activates protein kinase G. Inhibits thrombin-stimulated arachidonic acid release in human platelets.
Form
White solid
Intert gas (Yes/No)
Packaged under inert gas
CAS number
51116-01-9
Chemical formula
C₁₀H₁₀BrN₅O₇P · Na
Structure formula
Purity
≥98% by HPLC
Solubility
H₂O (200 mg/ml)
Storage
Protect from moisture -20°C Hygroscopic
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 1 week at -20°C.
Toxicity
Standard Handling
References
Kwak, B.R., and Jongsma, H.J. 1996. Mol. Cell. Biochem. 157, 93. Perreault, T., and DeMarte, J. 1993. Am. J. Physiol. 264, H302. Ruth, P., et al. 1991. Eur. J. Biochem.202, 1339. Schwarzschild, M.A., and Zigmond, R.E. 1991. J. Neurochem.56, 400.
Citation
Bing Zhu, Samuel Strada and Troy Stevens. (2005) Cyclic GMP-specific phosphodiesterase 5 regulates growth and apoptosis in pulmonary endothelial cells. American Journal of Physiology Lung Cellular and Molecular Physiology289, L196-L206.
