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330655 Estrogen Receptorα, Human, Recombinant, S. frugiperda

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: ER-α

330655
  
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      Overview

      Description
      Overview

      This product has been discontinued.




      We apologize for the inconvenience, but we do not currently have an alternative product.






      Recombinant, human estrogen receptor-α expressed in S. frugiperda insect cells. A hormone-inducible transcription factor that can positively or negatively regulate expression of many genes involved in tissue growth and differentiation. ER-α is essential for induction of the oxytocin receptor by estrogen. Activated ER-α is involved in the modulation of transcription triggered by AP-1. Provided in a soluble, functionally-active form. Binds to estradiol (Kd = 300 pM) and to a fluorescein-labeled estrogen response element (ERE; Kd = 10 nM). Suitable for in vitro transcription assays.
      Catalogue Number330655
      Brand Family Calbiochem®
      SynonymsER-α
      References
      ReferencesTeyssier, C., et al. 2001. J. Biol. Chem. 276, 36361.
      Young, L.T., et al. 1998. NeuroReport 9, 933.
      Tzukeman, M.T., et al. 1994. Mol. Endocrinol. 8, 21.
      Beekman, J.M., et al. 1993. Mol. Endocrinol. 7, 1266.
      Obourn, J.D., et al. 1993. Biochemistry 32, 6229.
      Product Information
      ActivityBinds ≥ 960 pmol/[³H]-estradiol/ml
      FormLiquid
      FormulationIn 500 mM KCl, 50 mM Tris, 2 mM DTT, 1 mM EDTA, 1 mM sodium vanadate, 10% glycerol, 0.02% NaN₃, pH 7.5.
      Biological Information
      Purity≥80% by SDS-PAGE
      Specific ActivityBinds ≥ 5,000 pmol [³H]-estradiol/mg protein
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C). DO NOT VORTEX.
      Global Trade Item Number
      Catalogue Number GTIN
      330655 0