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16-455 Anti-Phosphoserine Antibody, clone 4A4, HRP Conjugate

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16-455
10 blots  
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      Overview

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      AWBMHRPMonoclonal Antibody
      Description
      Catalogue Number16-455
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-Phosphoserine Antibody, clone 4A4, HRP Conjugate
      Alternate Names
      • 4A4
      • anti-phosphoserine
      • phosphoserine antibody
      • pan-phosphoserine
      Background InformationThe identification of protein phosphorylation as a regulatory mechanism originated from studies by Fischer and Krebs in the mid 1950s that later earned them the 1992 Nobel prize. It is the major mechanism for the regulation of diverse cellular processes including cell division, protein synthesis, transcriptional regulation and neurotrans-mission. The steady state phosphorylation of any given substrate is governed by the opposing activities of kinases and phosphatases. It is now believed that a third of all eukaryotic cellular proteins are phosphorylated and that over 95% of all phosphorylation events occur on serine and threonine residues.
      Product Information
      FormatHRP
      Presentation100 μL of protein G purified mouse IgG1 in PBS containing 0.05% Kathon® and HRP stabilizing compounds. Sufficient for a minimum of 10 immunoblots, if used at the optimum concentration of 1:4000 in 10 mL blocking buffer. Liquid.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Phosphoserine Antibody, clone 4A4, HRP Conjugate is an antibody against Phosphoserine for use in WB.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenPhosphoserine conjugated to KLH.
      Epitopephosphoserine
      Clone4A4
      HostMouse
      IsotypeIgG1
      Species Reactivity
      • All
      Species Reactivity NoteRecognizes proteins containing phosphoserine residues, regardless of origin.
      Antibody TypeMonoclonal Antibody
      Modifications
      • Phosphorylation
      Purification MethodProtein G Purified
      Molecular WeightVaries
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by western blot on RIPA lysates from insulin-treated human HEK293 cells.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at 2-8°C from date of shipment.
      NOTE: DO NOT FREEZE. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
      Packaging Information
      Material Size10 blots
      Global Trade Item Number
      Catalogue Number GTIN
      16-455 04053252589614