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MABS1963-100UG Anti-PEG Antibody, clone AGP3

MABS1963-100UG
100 μg  
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      Overview

      Replacement Information
      Description
      Catalogue NumberMABS1963-100UG
      DescriptionAnti-PEG Antibody, clone AGP3
      Alternate Names
      • Polyethylene Glycol
      Background InformationPolyethylene glycols (PEG) are non-toxic, uncharged, hydrophilic long chain polymers with a big exclusion volume in aqueous solution. The covalent attachment of PEG is commonly employed to modify proteins and drugs that can increase their bioavailability and reduce immunogenicity and proteolytic degradation. Clone AGP3 is a mouse monoclonal IgM antibody that displays high affinity to both short and long PEG molecules. It displays specificity for the repeating subunits present in PEG and can bind a broad range of PEG molecules. It is suitable for use as a capture antibody in ELISA with biotin-conjugated anti-PEG, clone 6.3 (Cat. No. MABS1966) as a detection reagent. Use of CHAPS detergent instead of Tween-20 is highly recommended in all washing buffers.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal antibody IgM in PBS with 0.04% sodium azide.
      Applications
      ApplicationAnti-PEG, clone AGP3, Cat. No. MABS1963, is a mouse monoclonal antibody that detects Polyethylene glycol (PEG) and has been tested for use in ELISA, Immunohistochemistry, and Western Blotting.
      Key Applications
      • ELISA
      • Immunohistochemistry
      • Western Blotting
      Application NotesWestern Blotting Analysis: A represenative lot detected PEG in Western Blotting applications (Cheng, T.L., et. al. (2005). Bioconjug Chem. 16(5):1225-31).

      ELISA Analysis: A represenative lot detected PEG in ELISA applications (Cheng, T.L., et. al. (2005). Bioconjug Chem. 16(5):1225-31).

      Immunohistochemistry Analysis: A represenative lot detected PEG in Immunohistochemistry applications (Ton, N.C., et. al. (2007). Clin Cancer Res. 13(23):7113-8).
      Biological Information
      ImmunogenPEG-conjugated to E.coli beta-glucuronidase.
      CloneAGP3
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      SpecificityClone AGP3 is a mouse monoclonal antibody with specificity for polyehtylene glycol backbone.
      IsotypeIgMκ
      Species Reactivity
      • All
      Species Reactivity NoteAll.
      Antibody TypeMonoclonal Antibody
      Purification MethodPurified by ion-exchange chromatography.
      Molecular WeightN/A
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by ELISA with immobilized Polyethylene Glycol (10K-PEG, 3K-PEG, and 2K-mPEG).

      ELISA Analysis: 20 µg/mL of Polyethylene Glycol (PEG) (10K-PEG, 3K-PEG, and 2K-mPEG) were detected by this antibody.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABS1963-100UG 04054839607820