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116816 Adenosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt - Calbiochem

Overview

Key Spec Table

Empirical Formula
C₁₀H₁₀BrN₅O₅PS · Na

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116816-5UMOL
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      Plastic ampoule 5 umol
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      Description
      OverviewA potent, cell-permeable, and reversible metabolically-stable cAMP antagonist that inhibits cAMP-dependent protein kinase and shows preference for PKA type I. More lipophilic than cAMP antagonist Rp-cAMPS (Cat. No. 116814).
      Note: 5 µmol = 2.23 mg.
      Catalogue Number116816
      Brand Family Calbiochem®
      SynonymsRp-8-Br-cAMPS, Na, PKA Inhibitor VI
      References
      ReferencesCalaghan, S.C., et al. 1999. Pflugers Arch. 437, 780.
      Gjertsen, B.T., et al. 1995. J. Biol. Chem. 270, 20599.
      Yokozaki, H., et al. 1992. Cancer Res. 52, 2504.
      Dostmann, W.R. et al. 1990. J. Biol. Chem. 265, 10484.
      Product Information
      ATP CompetitiveN
      DeclarationSold under license of Patent DE 3,802,865.4 issued to BIOLOG LSI.
      FormLyophilized
      Hill FormulaC₁₀H₁₀BrN₅O₅PS · Na
      Chemical formulaC₁₀H₁₀BrN₅O₅PS · Na
      Hygroscopic Hygroscopic
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetPKA 1
      Purity≥99% by HPLC
      Physicochemical Information
      Cell permeableY
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Global Trade Item Number
      Catalogue Number GTIN
      116816-5UMOL 04055977208269