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116802 Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶-Benzoyl-, Sodium Salt - CAS 30275-80-0 - Calbiochem

Overview

Key Spec Table

CAS #Empirical Formula
30275-80-0C₁₇H₁₅N₅O₇P · Na

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116802-10UMOL
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      Glass bottle 10 umol
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      Description
      OverviewA potent cell-permeable activator of cAMP-dependent protein kinase (PKA). Activates both type 1 and type 2 PKA and binds to the cAMP binding site 2 on the regulatory subunit of PKA. It is only slowly metabolized by cyclic nucleotide-dependent phosphodiesterases. Due to its considerably increased lipophilicity, it has sufficient membrane permeability for many biological systems.
      Note: 10 µmol = 4.55 mg.
      Catalogue Number116802
      Brand Family Calbiochem®
      Synonyms6-Bnz-cAMP, Na
      References
      ReferencesDøskeland, S.O., et al. 1993. Biochim. Biophys. Acta 1178, 249.
      Laurent-Cadoret, V., et al. 1993. Acta Endocrinol. 128, 555.
      Zorn, M., et al. 1993. Eur. J. Cell Biol. 60, 351.
      Product Information
      CAS number30275-80-0
      ATP CompetitiveN
      FormLyophilized
      Hill FormulaC₁₇H₁₅N₅O₇P · Na
      Chemical formulaC₁₇H₁₅N₅O₇P · Na
      Hygroscopic Hygroscopic
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      ApplicationAdenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶-Benzoyl-, Sodium Salt, CAS 30275-80-0, is a cell-permeable, potent activator of PKA type 1 & 2. Binds to the cAMP binding site 2 on the regulatory unit of PKA.
      Biological Information
      Primary TargetPKA
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableY
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Global Trade Item Number
      Catalogue Number GTIN
      116802-10UMOL 04055977208207