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681672 Sigma-AldrichWnt/β-catenin Inhibitor, Cardamonin - CAS 19309-14-9 - Calbiochem
The Wnt/β-catenin Inhibitor, Cardamonin, also referenced under CAS 19309-14-9, controls the biological activity of Wnt/β-catenin. This small molecule/inhibitor is primarily used for Cancer applications.
681668 Sigma-AldrichWnt Synergist, QS11 - CAS 944328-88-5 - Calbiochem
A cell-permeable purine compound that binds ARFGAPs (Kd = 364 and 620 nM for AMAP1 and ARFGAP1, respectively) and acts as a broad specificity ARFGAPs inhibitor (GTPase activating proteins of ADP-ribosylation factor).
681665 Sigma-AldrichWnt Agonist - CAS 853220-52-7 - Calbiochem
Wnt Agonist, CAS 853220-52-7, is a cell-permeable, potent, and selective activator of Wnt signaling. Does not inhibit the activity of GSK-3β (IC50 greater than 60 µM).
681671 Sigma-AldrichWnt Antagonist II, IWP-2 - CAS 686770-61-6 - Calbiochem
Wnt Antagonist II, IWP-2, CAS 686770-61-6, is a cell-permeable inhibitor of Wnt processing and secretion. Selectively blocks PORCN, a membrane-bound O-acyltransferase, & inhibits Wnt palmitoylation.
681669 Sigma-AldrichWnt Antagonist I, IWR-1-endo - Calbiochem
Wnt Antagonist I, IWR-1-endo, is a cell-permeable inhibitor of TNKS1/PARP5a (IC₅₀ = 131 nM) & TNKS2/PARP5b (IC₅₀= 56 nM). Suppress Wnt-stimulated transcription activity (IC₅₀ = 180 nM).
412400 Sigma-AldrichIQ-1 - CAS 331001-62-8 - Calbiochem
A cell-permeable tetrahydroisoquinolinylidene compound that modulates Wnt/β-catenin signaling by targeting the PR72/130 subunit of PP2A and thereby blocking PP2A/Nkd complex formation.
17-285 Sigma-AldrichTCF Reporter Plasmid Kit
Set of transfection grade T cell factor (TCF) reporter plasmids for use in TOPFlash and FOPFlash wnt/b-catenin activity assays.
09-162 Sigma-AldrichAnti-Wnt3A Antibody
Anti-Wnt3A Antibody is an antibody against Wnt3A for use in WB, IH(P).
361526 Sigma-AldrichGSK-3β, Rabbit Skeletal Muscle, Recombinant, E. coli
GSK-3β, Rabbit Skeletal MuscleHis-Tag®, Human, Recombinant, E. coli, is a dual specificity kinase that plays important roles in insulin- and Wnt-mediated signaling. It is inactivated by phosphorylation at Ser9.