Millipore Sigma Vibrant Logo

567375 Smac-N7 Peptide, Cell-Permeable - Calbiochem

The Smac-N7 peptide is modified to be cell permeant by linking the lysine carboxyl terminal to the arginine of Antennapedia homeodomain 16-mer peptide via a proline linker.

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: AVPIAQKPRQIKIWFQNRRMKWKK

Primary Target: Promotes procaspase-3 activation
View Products on Sigmaaldrich.com
567375
Ver precios y disponibilidad

Descripción

Replacement Information

Tabla espec. clave

Empirical Formula
C₁₄₂H₂₃₂N₄₄O₂₉S

Precios y disponibilidad

Número de referencia DisponiblidadEmbalaje Cant./Env. Precio Cantidad
567375-1MG
Comprobando disponibilidad...
—
Disponibilidad a confirmar Disponibilidad a confirmar
Ingrese cantidad 
Suspendido
Cantidades limitadas disponibles
Debe confirmarse disponibilidad
    El resto: se avisará
      El resto: se avisará
      Se avisará
      Póngase en contacto con el Servicio de Atención al Cliente
      Contact Customer Service

      		 Ampolla de plást. 1 mg
      Recuperando precio...
      No pudo obtenerse el precio
      La cantidad mínima tiene que ser múltiplo de
      Maximum Quantity is
      Al finalizar el pedido Más información
      Ahorró ()
       
      —
      Solicitar precio
      		 —
      Description
      OverviewThe Smac-N7 peptide (Cat. No. 567370) is modified to be cell permeant by linking the lysine carboxyl terminal to the arginine of Antennapedia homeodomain 16-mer peptide via a proline linker.
      Catalogue Number567375
      Brand Family Calbiochem®
      SynonymsAVPIAQKPRQIKIWFQNRRMKWKK
      References
      ReferencesSrinivasula, S.M., et al. 2001. Nature 410, 112.
      Chai, J., et al. 2000. Nature 406, 855.
      Liu, Z., et al. 2000. Nature 408, 1004.
      Srinivasula, S.M., et al. 2000. J. Biol. Chem. 275, 36152.
      Product Information
      ATP CompetitiveN
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₁₄₂H₂₃₂N₄₄O₂₉S
      Chemical formulaC₁₄₂H₂₃₂N₄₄O₂₉S
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPromotes procaspase-3 activation
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Peptide SequenceH-Ala-Val-Pro-Ile-Ala-Gln-Lys-Pro-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-OH
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      567375-1MG 07790788051594

      Documentation

      Smac-N7 Peptide, Cell-Permeable - Calbiochem Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Smac-N7 Peptide, Cell-Permeable - Calbiochem Certificados de análisis

      CargoNúmero de lote
      567375

      Referencias bibliográficas

      Visión general referencias
      Srinivasula, S.M., et al. 2001. Nature 410, 112.
      Chai, J., et al. 2000. Nature 406, 855.
      Liu, Z., et al. 2000. Nature 408, 1004.
      Srinivasula, S.M., et al. 2000. J. Biol. Chem. 275, 36152.

      Folleto

      Cargo
      Caspases and other Apoptosis Related Tools Brochure
      Ficha técnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision11-September-2008 RFH
      SynonymsAVPIAQKPRQIKIWFQNRRMKWKK
      DescriptionThe Smac-N7 peptide (Cat. No. 567370) where the lysine carboxy terminal is linked to the arginine of Antennapedia homeodomain 16-mer peptide (underlined) via a proline linker to make it cell-permeable. Smac-N7 peptide contains the N-terminal seven residues of Smac and promotes the activation of procaspase-3 (~10 µM). Also, promotes the catalytic activity of caspase-9 in the presence of XIAP.
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₁₄₂H₂₃₂N₄₄O₂₉S
      Peptide SequenceH-Ala-Val-Pro-Ile-Ala-Gln-Lys-Pro-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-OH
      Purity≥95% by HPLC
      SolubilityDMSO (5 mg/ml)
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesSrinivasula, S.M., et al. 2001. Nature 410, 112.
      Chai, J., et al. 2000. Nature 406, 855.
      Liu, Z., et al. 2000. Nature 408, 1004.
      Srinivasula, S.M., et al. 2000. J. Biol. Chem. 275, 36152.