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14-581 Ron Protein, active, 10 µg

Active, N-terminal GST-tagged, recombinant, human Ron amino acids 983-end, for use in Kinase Assays.

Ron Protein, active, 10 µg: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
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14-581
10 µg  Also available in 250 µg size --call for pricing and availability and reference catalog number 14-581M when ordering the 250 µg size.
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      Descripción

      Replacement Information
      Description
      Catalogue Number14-581
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionRon Protein, active, 10 µg
      OverviewN-terminal GST-tagged, recombinant, human Ron amino acids 983-end
      References
      Product Information
      Quality LevelMQ100
      Applications
      ApplicationActive, N-terminal GST-tagged, recombinant, human Ron amino acids 983-end, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      Sourceexpressed by baculovirus in Sf21 insect cells
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme
      Entrez Gene Number
      Gene Symbol
      • MST1R
      • CDw136
      • RON
      • PTK8
      • p185-Ron
      Protein TargetRon
      Purification MethodGlutathione agarose affinity chromatography
      Target Sub-FamilyTK
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q04912 # Receptor for macrophage stimulating protein (MSP). Has a tyrosine-protein kinase activity.
      SIZE: 1400 amino acids; 152227 Da
      SUBUNIT: Heterodimer formed of an alpha chain and a beta chain which are disulfide linked. Binds PLXNB1. Associates with and is negatively regulated by HYAL2.
      SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
      TISSUE SPECIFICITY: Keratinocytes and lung.
      PTM: Proteolytic processing yields the two subunits. & Phosphorylated in response to ligand binding (Probable).
      SIMILARITY: SwissProt: Q04912 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. & Contains 3 IPT/TIG domains. & Contains 1 protein kinase domain. & Contains 1 Sema domain.
      Molecular Weight74.2kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by phosphorylating Axltide (Catalog #12-516)
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C
      Packaging Information
      Material Size10 µg
      Material PackageAlso available in 250 µg size --call for pricing and availability and reference catalog number 14-581M when ordering the 250 µg size.
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      14-581 04053252322952