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539162 Proteasome Inhibitor II - Calbiochem

The Proteasome Inhibitor II controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Proteasome Inhibitor II - Calbiochem: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: (Benzyloxycarbonyl)-Leu-Leu-phenylalaninal, Z-LLF-CHO

Primary Target: MPC
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539162
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Descripción

Replacement Information

Tabla espec. clave

Empirical Formula
C₂₉H₃₉N₃O₅

Precios y disponibilidad

Número de referencia DisponiblidadEmbalaje Cant./Env. Precio Cantidad
539162-1MG
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      539162-5MG
      Comprobando disponibilidad...
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      Disponibilidad a confirmar Disponibilidad a confirmar
      Ingrese cantidad 
      Suspendido
      Cantidades limitadas disponibles
      Debe confirmarse disponibilidad
        El resto: se avisará
          El resto: se avisará
          Se avisará
          Póngase en contacto con el Servicio de Atención al Cliente
          Contact Customer Service

          		 Ampolla de plást. 5 mg
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          No pudo obtenerse el precio
          La cantidad mínima tiene que ser múltiplo de
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          Description
          OverviewA potent, cell-permeable, and reversible proteasome inhibitor. Inhibits the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex (MPC; Ki = 460 nM). Does not inhibit the peptidyl-glutamyl peptide hydrolyzing activity of MPC even at concentrations of 200 µM. Also blocks the decay of IκB-α and IκB-β proteins in exponentially growing WEHI 231 cells.
          Catalogue Number539162
          Brand Family Calbiochem®
          Synonyms(Benzyloxycarbonyl)-Leu-Leu-phenylalaninal, Z-LLF-CHO
          References
          ReferencesSchauer, S.L., et al. 1998. J. Immunol. 160, 4398.
          Orlowski, M., et al. 1997. Biochemistry 36, 13946.
          Orlowski, M., et al. 1993. Biochemistry 32, 1563.
          Product Information
          ATP CompetitiveN
          FormWhite lyophilized solid
          Hill FormulaC₂₉H₃₉N₃O₅
          Chemical formulaC₂₉H₃₉N₃O₅
          ReversibleY
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetMPC
          Primary Target K<sub>i</sub>460 nM against the pituitary multicatalytic proteinase complex (MPC)
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableY
          Peptide SequenceZ-Leu-Leu-Phe-CHO
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Moisture Protect from moisture
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Número de referencia GTIN
          539162-1MG 04055977269451
          539162-5MG 04055977269468

          Documentation

          Proteasome Inhibitor II - Calbiochem Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          Proteasome Inhibitor II - Calbiochem Certificados de análisis

          CargoNúmero de lote
          539162

          Referencias bibliográficas

          Visión general referencias
          Schauer, S.L., et al. 1998. J. Immunol. 160, 4398.
          Orlowski, M., et al. 1997. Biochemistry 36, 13946.
          Orlowski, M., et al. 1993. Biochemistry 32, 1563.

          Folleto

          Cargo
          Caspases and other Apoptosis Related Tools Brochure
          Proteasomes Technical Bulletin
          Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision04-September-2008 RFH
          Synonyms(Benzyloxycarbonyl)-Leu-Leu-phenylalaninal, Z-LLF-CHO
          DescriptionA potent and cell-permeable proteasome inhibitor. Inhibits the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex (MPC; Ki = 460 nM). Does not inhibit the peptidylglutamyl-peptide hydrolyzing (PGPH) activity of MPC even at concentrations of 200 µM. Also blocks the decay of IκB-α and IκB-β proteins in exponentially growing WEHI 231 cells.
          FormWhite lyophilized solid
          Chemical formulaC₂₉H₃₉N₃O₅
          Peptide SequenceZ-Leu-Leu-Phe-CHO
          Purity≥95% by HPLC
          SolubilityDMSO (5 mg/ml)
          Storage Protect from moisture
          -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months.
          Toxicity Standard Handling
          ReferencesSchauer, S.L., et al. 1998. J. Immunol. 160, 4398.
          Orlowski, M., et al. 1997. Biochemistry 36, 13946.
          Orlowski, M., et al. 1993. Biochemistry 32, 1563.