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524736 Phosphodiesterase 4B2, His•Tag®, Human, Recombinant, S. frugiperda

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: PDE4B2, cAMP-Specific Phosphodiesterase 4B2

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524736
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Descripción

Replacement Information

Precios y disponibilidad

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524736-10U
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      Description
      OverviewFull-length, recombinant, human phosphodiesterase 4B2 (accession no. L20971) fused at the N-terminus to a His•Tag® sequence and expressed in S. frugiperda using a baculovirus expression system. Plays a significant role in the regulation of inflammatory cell activation. PDE4B2 is a predominant isoform in neutrophils and monocytes. Supplied as a partially purified, catalytically active preparation.
      Catalogue Number524736
      Brand Family Calbiochem®
      SynonymsPDE4B2, cAMP-Specific Phosphodiesterase 4B2
      Application Data
      Phosphodiesterase 4B2 was treated with increasing concentrations of the inhibitor, rolipram, and the activity assayed. the IC50 for this inhibition is 1.77 µM.
      References
      ReferencesGibson, L.C.D., et al. 2006. Eur. J. Pharmacol. 538, 39.
      Smith, P.G., et al. 2005 Blood 105, 308.
      Baroja, M.L., et al. 1999. J. Immunol. 162, 2016.
      Product Information
      Activity≥ 0.25 units/µl
      Unit of DefinitionOne unit is defined as the amount of enzyme that will convert 1 pmol cAMP to AMP per min at 30°C, pH 7.5.
      FormLiquid
      FormulationIn 150 mM NaCl, 10 mM Tris, 0.1% NP-40, pH 8.3.
      Quality LevelMQ100
      Applications
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      524736-10U 04055977197709

      Documentation

      Phosphodiesterase 4B2, His•Tag®, Human, Recombinant, S. frugiperda Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Phosphodiesterase 4B2, His•Tag®, Human, Recombinant, S. frugiperda Certificados de análisis

      CargoNúmero de lote
      524736

      Referencias bibliográficas

      Visión general referencias
      Gibson, L.C.D., et al. 2006. Eur. J. Pharmacol. 538, 39.
      Smith, P.G., et al. 2005 Blood 105, 308.
      Baroja, M.L., et al. 1999. J. Immunol. 162, 2016.
      Ficha técnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision10-March-2009 JSW
      SynonymsPDE4B2, cAMP-Specific Phosphodiesterase 4B2
      Application Data
      Phosphodiesterase 4B2 was treated with increasing concentrations of the inhibitor, rolipram, and the activity assayed. the IC50 for this inhibition is 1.77 µM.
      DescriptionFull-length, recombinant, human phosphodiesterase 4B2 (accession no. L20971) fused at the N-terminus to a His•Tag® sequence and expressed in S. frugiperda using a baculovirus expression system. Plays a significant role in the regulation of inflammatory cell activation. PDE4B2 is a predominant isoform in neutrophils and monocytes. Supplied as a partially purified, catalytically active preparation.
      FormLiquid
      FormulationIn 150 mM NaCl, 10 mM Tris, 0.1% NP-40, pH 8.3.
      Activity≥ 0.25 units/µl
      Unit definitionOne unit is defined as the amount of enzyme that will convert 1 pmol cAMP to AMP per min at 30°C, pH 7.5.
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesGibson, L.C.D., et al. 2006. Eur. J. Pharmacol. 538, 39.
      Smith, P.G., et al. 2005 Blood 105, 308.
      Baroja, M.L., et al. 1999. J. Immunol. 162, 2016.