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444278 MMP-9 Inhibitor I - CAS 1177749-58-4 - Calbiochem

MMP-9 Inhibitor I, CAS 1177749-58-4, is a cell-permeable, potent, and reversible MMP-9 Inhibitor (IC₅₀ = 5 nM). At high concentration inhibits MMP-1 (IC₅₀ = 1.05 µM) & MMP-13 (IC₅₀ = 113 nM).

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Primary Target: MMP-9
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444278
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Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
1177749-58-4C₂₇H₃₃N₃O₅S

Precios y disponibilidad

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444278-500UG
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      Description
      OverviewA cell-permeable, potent, selective, and reversible MMP-9 Inhibitor (IC50 = 5 nM). Inhibits MMP-1 (IC50 = 1.05 µM) and MMP-13 (IC50 = 113 nM) only at much higher concentrations.
      Catalogue Number444278
      Brand Family Calbiochem®
      References
      ReferencesLevin, J.I., et al. 2001. Bioorg. Med. Chem. Lett. 11, 2189.
      Product Information
      CAS number1177749-58-4
      ATP CompetitiveN
      FormOff-white solid
      Hill FormulaC₂₇H₃₃N₃O₅S
      Chemical formulaC₂₇H₃₃N₃O₅S
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetMMP-9
      Primary Target IC<sub>50</sub>5 nM
      Purity≥93% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      444278-500UG 04055977186598

      Documentation

      MMP-9 Inhibitor I - CAS 1177749-58-4 - Calbiochem Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      MMP-9 Inhibitor I - CAS 1177749-58-4 - Calbiochem Certificados de análisis

      CargoNúmero de lote
      444278

      Referencias bibliográficas

      Visión general referencias
      Levin, J.I., et al. 2001. Bioorg. Med. Chem. Lett. 11, 2189.

      Citas

      Título
    • White A.R, et al. 2006. journal of Biological Chemistry 281, 17670.
    • Michelle K.Y. Siu and C. Yan Cheng. 2004. Biology of Reproduction 70, 945.
    • Lubbe, WL, et al. 2006. Clin. Cancer Res. 12 1876.
      		•
      Ficha técnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-April-2011 RFH
      DescriptionA cell-permeable, potent, selective, and reversible inhibitor of MMP-9 (IC50 = 5 nM). Also inhibits MMP-1 (IC50 = 1.05 µM) and MMP-13 IC50 = 113 nM) at higher concentrations.
      FormOff-white solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number1177749-58-4
      Chemical formulaC₂₇H₃₃N₃O₅S
      Structure formulaStructure formula
      Purity≥93% by HPLC
      SolubilityDMSO (10 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesLevin, J.I., et al. 2001. Bioorg. Med. Chem. Lett. 11, 2189.
      Citation
    • White A.R, et al. 2006. journal of Biological Chemistry 281, 17670.
    • Michelle K.Y. Siu and C. Yan Cheng. 2004. Biology of Reproduction 70, 945.
    • Lubbe, WL, et al. 2006. Clin. Cancer Res. 12 1876.
      		•