Millipore Sigma Vibrant Logo

05-23-3800 Endothelin 1, Human and Porcine - CAS 117399-94-7 - Calbiochem

Endothelin 1, Human and Porcine, CAS 117399-94-7, is a 21-amino acid polypeptide with potent vasoconstrictive action. Activates phospholipase C in fibroblasts expressing ETA receptors.

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: ET-1, CSCSSLMDKECVYFCHLDIIW

Primary Target: Potent vasoconstrictive action
View Products on Sigmaaldrich.com
05-23-3800
Ver precios y disponibilidad

Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
117399-94-7C₁₀₉H₁₅₉N₂₅O₃₂S₅

Precios y disponibilidad

Número de referencia DisponiblidadEmbalaje Cant./Env. Precio Cantidad
US105233800-0.1MG
Comprobando disponibilidad...
—
Disponibilidad a confirmar Disponibilidad a confirmar
Ingrese cantidad 
Suspendido
Cantidades limitadas disponibles
Debe confirmarse disponibilidad
    El resto: se avisará
      El resto: se avisará
      Se avisará
      Póngase en contacto con el Servicio de Atención al Cliente
      Contact Customer Service

      		 Ampolla de plást. .1 mg
      Recuperando precio...
      No pudo obtenerse el precio
      La cantidad mínima tiene que ser múltiplo de
      Maximum Quantity is
      Al finalizar el pedido Más información
      Ahorró ()
       
      —
      Solicitar precio
      		 —
      US105233800-0.5MG
      Comprobando disponibilidad...
      —
      Disponibilidad a confirmar Disponibilidad a confirmar
      Ingrese cantidad 
      Suspendido
      Cantidades limitadas disponibles
      Debe confirmarse disponibilidad
        El resto: se avisará
          El resto: se avisará
          Se avisará
          Póngase en contacto con el Servicio de Atención al Cliente
          Contact Customer Service

          		 Ampolla de plást. .5 mg
          Recuperando precio...
          No pudo obtenerse el precio
          La cantidad mínima tiene que ser múltiplo de
          Maximum Quantity is
          Al finalizar el pedido Más información
          Ahorró ()
           
          —
          Solicitar precio
          		 —
          Description
          OverviewA 21-amino acid polypeptide with potent vasoconstrictive action. Produces convulsions, arterial hypertension, and metabolic activation of periventricular white and gray matter. Its effects are mediated via L-type Ca2+ channels. Reported to activate phospholipase C in fibroblasts expressing ETA receptors.
          Catalogue Number05-23-3800
          Brand Family Calbiochem®
          SynonymsET-1, CSCSSLMDKECVYFCHLDIIW
          References
          ReferencesCesari, M., et al. 1996. Am. Heart J. 132, 1236.
          Gresser, O., et al 1996. Biochem. Biophys. Res. Commun. 224, 169.
          Murata, S., et al. 1995. J. Pharmacol. Exp. Ther. 274, 1524.
          Hexum, T.D., et al. 1990. Biochem. Biophys. Res. Commun. 167, 294.
          Itoh, Y., et al. 1988. FEBS Lett. 231, 440.
          Yanagisawa, M., et al. 1988. Nature 332, 411.
          Product Information
          CAS number117399-94-7
          ATP CompetitiveN
          FormWhite to off-white solid
          FormulationSupplied as an acetate salt.
          Hill FormulaC₁₀₉H₁₅₉N₂₅O₃₂S₅
          Chemical formulaC₁₀₉H₁₅₉N₂₅O₃₂S₅
          ReversibleN
          Sold on the basis of peptide contentY
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetPotent vasoconstrictive action
          Purity≥96% by HPLC
          Physicochemical Information
          Cell permeableN
          Peptide ContentY
          Peptide SequenceH-Cys¹-Ser-Cys³-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys¹¹-Val-Tyr-Phe-Cys¹⁵-His-Leu-Asp-Ile-Ile-Trp-OH (disulfide bonds: 1 → 15; 3 → 11)
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Moisture Protect from moisture
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 weeks at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Número de referencia GTIN
          US105233800-0.1MG 04055977226775
          US105233800-0.5MG 04055977226782

          Documentation

          Licencias necesarias

          Título
          CARTA DE USO GENERAL 2016
          PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

          Endothelin 1, Human and Porcine - CAS 117399-94-7 - Calbiochem Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          Endothelin 1, Human and Porcine - CAS 117399-94-7 - Calbiochem Certificados de análisis

          CargoNúmero de lote
          05-23-3800

          Referencias bibliográficas

          Visión general referencias
          Cesari, M., et al. 1996. Am. Heart J. 132, 1236.
          Gresser, O., et al 1996. Biochem. Biophys. Res. Commun. 224, 169.
          Murata, S., et al. 1995. J. Pharmacol. Exp. Ther. 274, 1524.
          Hexum, T.D., et al. 1990. Biochem. Biophys. Res. Commun. 167, 294.
          Itoh, Y., et al. 1988. FEBS Lett. 231, 440.
          Yanagisawa, M., et al. 1988. Nature 332, 411.
          Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision12-May-2008 JSW
          SynonymsET-1, CSCSSLMDKECVYFCHLDIIW
          DescriptionA 21 amino acid polypeptide with potent vasoconstrictive action. Produces convulsions, arterial hypertension, and metabolic activation of periventricular white and gray matter. Its effects are mediated via L-type Ca2+ channels. Reported to activate phospholipase C in fibroblasts expressing ETA receptors.
          FormWhite to off-white solid
          FormulationSupplied as an acetate salt.
          CAS number117399-94-7
          Chemical formulaC₁₀₉H₁₅₉N₂₅O₃₂S₅
          Peptide SequenceH-Cys¹-Ser-Cys³-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys¹¹-Val-Tyr-Phe-Cys¹⁵-His-Leu-Asp-Ile-Ile-Trp-OH (disulfide bonds: 1 → 15; 3 → 11)
          Purity≥96% by HPLC
          Solubility5% Acetic acid (0.5 mg/ml). Dissolve peptide initially at 8 mg/ml in 80% cold acetic acid, then dilute with distilled water to achieve 5% acetic acid and 0.5 mg/ml peptide.
          Storage Protect from moisture
          -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 weeks at -20°C.
          Toxicity Standard Handling
          ReferencesCesari, M., et al. 1996. Am. Heart J. 132, 1236.
          Gresser, O., et al 1996. Biochem. Biophys. Res. Commun. 224, 169.
          Murata, S., et al. 1995. J. Pharmacol. Exp. Ther. 274, 1524.
          Hexum, T.D., et al. 1990. Biochem. Biophys. Res. Commun. 167, 294.
          Itoh, Y., et al. 1988. FEBS Lett. 231, 440.
          Yanagisawa, M., et al. 1988. Nature 332, 411.