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218750 Caspase-3 Inhibitor III - CAS 285570-60-7 - Calbiochem

Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
285570-60-7C₂₁H₃₁ClN₄O₁₁

Precios y disponibilidad

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218750-1MG
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      218750-5MG
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      Disponibilidad a confirmar
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      Ingrese cantidad 
      Suspendido
      Cantidades limitadas disponibles
      Debe confirmarse disponibilidad
        El resto: se avisará
          El resto: se avisará
          Se avisará
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          Contact Customer Service

          Ampolla de plást. 5 mg
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          Description
          OverviewA potent, cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, caspase-7, caspase-8, and caspase-10.
          Catalogue Number218750
          Brand Family Calbiochem®
          SynonymsAc-DEVD-CMK
          References
          ReferencesMocanu, M.M., et al. 2000. Br. J. Pharmacol. 130, 197
          Schrantz, N., et al. 1999. Cell Death Differ. 6, 445.
          Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
          Product Information
          CAS number285570-60-7
          ATP CompetitiveN
          FormWhite to off-white lyophilized solid or powder
          Hill FormulaC₂₁H₃₁ClN₄O₁₁
          Chemical formulaC₂₁H₃₁ClN₄O₁₁
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary Targetcaspase-3, caspase-6, caspase-7, caspase-8, caspase-10
          Purity≥98% by HPLC
          Physicochemical Information
          Cell permeableY
          Peptide SequenceAc-Asp-Glu-Val-Asp-CMK
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Moisture Protect from moisture
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Número de referencia GTIN
          218750-1MG 04055977219074
          218750-5MG 04055977219081

          Documentation

          Caspase-3 Inhibitor III - CAS 285570-60-7 - Calbiochem Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          Caspase-3 Inhibitor III - CAS 285570-60-7 - Calbiochem Certificados de análisis

          CargoNúmero de lote
          218750

          Referencias bibliográficas

          Visión general referencias
          Mocanu, M.M., et al. 2000. Br. J. Pharmacol. 130, 197
          Schrantz, N., et al. 1999. Cell Death Differ. 6, 445.
          Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.

          Folleto

          Cargo
          Caspases and other Apoptosis Related Tools Brochure

          Citas

          Título
        • Yumin Zhang, et al. (2004) Peroxynitrite-Induced Neuronal Apoptosis is Mediated by Intracellular Zinc Release and 12-Lipoxygenase Activation. Journal of Neuroscience 24, 10616-10627.
        • Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision09-April-2018 JSW
          SynonymsAc-DEVD-CMK
          DescriptionA potent cell-permeable and irreversible inhibitor of caspase-3, a member of the ICE-CED-3 family of cysteine proteases.
          FormWhite to off-white lyophilized solid or powder
          CAS number285570-60-7
          Chemical formulaC₂₁H₃₁ClN₄O₁₁
          Peptide SequenceAc-Asp-Glu-Val-Asp-CMK
          Structure formulaStructure formula
          Purity≥98% by HPLC
          Solubility20% Acetonitrile (in H₂O) (1 mg/ml)
          Storage Protect from moisture
          -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
          Toxicity Standard Handling
          ReferencesMocanu, M.M., et al. 2000. Br. J. Pharmacol. 130, 197
          Schrantz, N., et al. 1999. Cell Death Differ. 6, 445.
          Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
          Citation
        • Yumin Zhang, et al. (2004) Peroxynitrite-Induced Neuronal Apoptosis is Mediated by Intracellular Zinc Release and 12-Lipoxygenase Activation. Journal of Neuroscience 24, 10616-10627.