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MAB3494 Anti-ATP Synthase Antibody, β chain, clone 4.3E8.D1

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MAB3494
100 µg  
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      Descripción

      Replacement Information

      Ofertas especiales

      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RICC, IPMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMAB3494
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-ATP Synthase Antibody, β chain, clone 4.3E8.D1
      Alternate Names
      • Mitochondrial Marker
      References
      Product Information
      FormatPurified
      PresentationPurified immunoglobulin. Liquid in 0.02M Phosphate buffer, 0.25M NaCl with 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-ATP Synthase Antibody, β chain, clone 4.3E8.D1 detects level of ATP Synthase & has been published & validated for use in IC & IP.
      Key Applications
      • Immunocytochemistry
      • Immunoprecipitation
      Application NotesImmunocytochemistry: 1 μg/mL for one hour at room temperature using 10xE6 cells or adherent sample by indirect immunofluorescence. Suggested fixative is 2-4% paraformaldehyde. Suggested permeabilization method is 0.5% Triton X-100.

      Immunoprecipitation

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenRat brain mitochondria
      Epitopebeta chain
      Clone4.3E8.D1
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityRecognizes the beta chain of ATP Synthase. The beta chain of ATP Synthase is a useful subcellular marker for mitochondria.
      IsotypeIgG1
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the beta subunit of the catalytic core.
      Gene Symbol
      • ATP5B
      • ATPMB
      • ATPSB
      • MGC5231
      • EC 3.6.3.14
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P06576 # Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is the catalytic subunit.
      SIZE: 529 amino acids; 56560 Da
      SUBUNIT: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
      SUBCELLULAR LOCATION: Mitochondrion.
      SIMILARITY: SwissProt: P06576 ## Belongs to the ATPase alpha/beta chains family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      MAB3494 04053252466731

      Documentation

      Anti-ATP Synthase Antibody, β chain, clone 4.3E8.D1 Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Anti-ATP Synthase Antibody, β chain, clone 4.3E8.D1 Certificados de análisis

      CargoNúmero de lote
      MOUSE ANTI-ATP SYNTHASE, BETA CHAIN MONOCLONAL ANTIBODY - 2433368 2433368
      MOUSE ANTI-ATP SYNTHASE, BETA CHAIN - 3170821 3170821
      MOUSE ANTI-ATP SYNTHASE, BETA CHAIN - 3305927 3305927
      MOUSE ANTI-ATP SYNTHASE, BETA CHAIN - 3717722 3717722
      MOUSE ANTI-ATP SYNTHASE, BETA CHAIN - 3776188 3776188
      MOUSE ANTI-ATP SYNTHASE, BETA CHAIN - 3876880 3876880
      MOUSE ANTI-ATP SYNTHASE, BETA CHAIN - 3958867 3958867
      MOUSE ANTI-ATP SYNTHASE, BETA CHAIN - 3995167 3995167
      MOUSE ANTI-ATP SYNTHASE, BETA CHAIN - 4045883 4045883
      MOUSE ANTI-ATP SYNTHASE, BETA CHAIN - 4164236 4164236

      Referencias bibliográficas

      Visión general referenciasPub Med ID
      Endothelin-1 induces LIMK2-mediated programmed necrotic neuronal death independent of NOS activity.
      Ko, AR; Hyun, HW; Min, SJ; Kim, JE; Kang, TC
      Molecular brain  8  58  2015

      Mostrar resumen
      26438559 26438559
      Cytomegalovirus-induced embryopathology: mouse submandibular salivary gland epithelial-mesenchymal ontogeny as a model.
      Melnick, M; Mocarski, ES; Abichaker, G; Huang, J; Jaskoll, T
      BMC developmental biology  6  42  2005

      Mostrar resumen
      16959038 16959038
      Proteomic identification of the involvement of the mitochondrial rieske protein in epilepsy.
      Heike Junker, Kira Späte, Yalikun Suofu, Reinhard Walther, Gerold Schwarz, Winfried Kammer, Alfred Nordheim, Lary C Walker, Uwe Runge, Christof Kessler, Aurel Popa-Wagner
      Epilepsia  46  339-43  2004

      Mostrar resumen
      15730530 15730530

      Ficha técnica

      Cargo
      MOUSE ANTI-ATP SYNTHASE, BETA CHAIN