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251700 1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride - Calbiochem

1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride, is an irreversible inhibitor of uPA, Factor Xa & urokinase. Does not inhibit tPA.

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: 1,5-DNS-GGACK, 2HCl

Primary Target: UPA
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251700
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      Description
      OverviewEffective irreversible inhibitor of uPA, Factor Xa, and urokinase. Fluorophore allows direct monitoring of interactions of labeled enzyme. Does not inhibit tPA.
      Catalogue Number251700
      Brand Family Calbiochem®
      Synonyms1,5-DNS-GGACK, 2HCl
      References
      ReferencesBajaj, S.P., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 152.
      Bergmeyer, H.V. 1984. Methods Enzym. Anal. 5, 375.
      Kettner, C., and Shaw, E. 1981. Methods Enzymol. 80, 826.
      Product Information
      ATP CompetitiveN
      FormOff-white solid
      ReversibleN
      Quality LevelMQ100
      Applications
      Application1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride, is an irreversible inhibitor of uPA, Factor Xa & urokinase. Does not inhibit tPA.
      Biological Information
      Primary TargetUPA
      Primary Target IC<sub>50</sub>100 nM for factor Xa
      Physicochemical Information
      Cell permeableN
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.
      Global Trade Item Number
      Número de referencia GTIN
      251700-5MG 04055977217957