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20-148 Sigma-AldrichHAT Assay Buffer, 5X
For use in the HAT Assay.
14-418 Sigma-Aldrichp300, HAT Domain
Recombinant GST-fusion protein corresponding to amino acids 1066-1707 of human p300.
324880 Sigma-Aldrich(–)-Epigallocatechin Gallate - CAS 989-51-5 - Calbiochem
One of the main polyphenolic constituents of green tea that exhibits potent antitumor, anti-inflammatory, and antioxidant properties.
14-309 Sigma-AldrichPCAF Protein, Active, 50 µg
PCAF recombinant GST fusion protein, for use in Histone Acetyltransferase Assays. (HAT).
567860 Sigma-AldrichSRT1720 - CAS 925434-55-5 - Calbiochem
SRT1720, CAS 925434-55-5, is a cell-permeable inhibitor of the mitochondrial SIRT3. Inhibition is AceCS2-competitive (Ki = 0.56 µM; Km = 2.44 µM), but NAD+-uncompetitive (Ki = 0.34 µM; Km = 280 µM).
382110 Sigma-AldrichHistone Acetyltransferase Inhibitor II - CAS 932749-62-7 - Calbiochem
The Histone Acetyltransferase Inhibitor II, also referenced under CAS 932749-62-7, controls the biological activity of Histone Acetyltransferase. This small molecule/inhibitor is primarily used for Cell Structure applications.
345887 Sigma-AldrichGinkgolic Acid (15:1) - CAS 22910-60-7 - Calbiochem
Ginkgolic Acid (15:1), CAS 22910-60-7, is a cell-permeable analog of anacardic acid that inhibits protein SUMOylation (IC50 = 3.0 µM using RanGAP1-C2 as substrate) in an ATP-dependent manner.
13-107 Sigma-AldrichCore Histones
Highly pure core histones proteins (H2A, H2B, H3 and H4) including H1 purified from chicken erythrocytes, suitable as a substrate for histone modification assays (HAT, HDAC, DNMT) and nucleosome assembly studies.
172050 Sigma-AldrichAnacardic Acid - CAS 16611-84-0 - Calbiochem
Anacardic Acid, CAS 16611-84-0, is a cell-permeable ginkgolic acid analog that targets SUMO-activating enzyme E1 and inhibits protein SUMO modification (IC50 = 2.2 µM) in an ATP-dependent manner.
239802 Sigma-AldrichCurcumin, Curcuma longa L. - CAS 458-37-7 - Calbiochem
A cell-permeable and irreversible antitumor and anti-inflammatory agent that acts as an inhibitor of 5-lipoxygenase (IC₅₀ = 8 µM) and cyclooxygenase (IC₅₀ = 52 µM).