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565950 Sialyl Lewis x, Sodium Salt - CAS 98603-84-0 - Calbiochem

Enzymatically prepared tetrasaccharide which acts as a minimal binding ligand for E-selectins.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: SLex, Neu5Acα2,3Galβ1,4(Fucα1,3)GlcNAc

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565950
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
98603-84-0C₃₁H₅₁NaN₂O₂₃

Pricing & Availability

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565950-5MG
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      Description
      OverviewEnzymatically prepared tetrasaccharide which acts as a minimal binding ligand for E-selectins. SLex reduces injury following ischemia and reperfusion and immune complex-induced acute lung injury in animal models. In both of these models, SLex is presumed to act by blocking E-selectin-mediated neutrophil recruitment to sites of inflammation.
      Catalogue Number565950
      Brand Family Calbiochem®
      SynonymsSLex, Neu5Acα2,3Galβ1,4(Fucα1,3)GlcNAc
      References
      ReferencesSeekamp, A., et al. 1994. Am. J. Pathol. 144, 592.
      Mulligan, M.S., et al. 1993. J. Exp. Med. 178, 623.
      Ichikawa, Y., et al. 1992. J. Am. Chem. Soc. 114, 9283.
      Lasky, L.A. 1992. Science 258, 964.
      Product Information
      CAS number98603-84-0
      FormWhite solid
      Hill FormulaC₃₁H₅₁NaN₂O₂₃
      Chemical formulaC₃₁H₅₁NaN₂O₂₃
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by TLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      565950-5MG 04055977191318

      Documentation

      Sialyl Lewis x, Sodium Salt - CAS 98603-84-0 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Sialyl Lewis x, Sodium Salt - CAS 98603-84-0 - Calbiochem Certificates of Analysis

      TitleLot Number
      565950

      References

      Reference overview
      Seekamp, A., et al. 1994. Am. J. Pathol. 144, 592.
      Mulligan, M.S., et al. 1993. J. Exp. Med. 178, 623.
      Ichikawa, Y., et al. 1992. J. Am. Chem. Soc. 114, 9283.
      Lasky, L.A. 1992. Science 258, 964.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision10-September-2008 RFH
      SynonymsSLex, Neu5Acα2,3Galβ1,4(Fucα1,3)GlcNAc
      DescriptionEnzymatically prepared tetrasaccharide which acts as a minimal binding ligand for E-selectins. SLex reduces injury following ischemia, reperfusion and immune complex-induced acute lung injury in animal models. In both of these models, SLex is presumed to act by blocking E-selectin-mediated neutrophil recruitment to sites of inflammation.
      FormWhite solid
      CAS number98603-84-0
      Chemical formulaC₃₁H₅₁NaN₂O₂₃
      Structure formulaStructure formula
      Purity≥95% by TLC
      SolubilityH₂O (2 mg/ml)
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesSeekamp, A., et al. 1994. Am. J. Pathol. 144, 592.
      Mulligan, M.S., et al. 1993. J. Exp. Med. 178, 623.
      Ichikawa, Y., et al. 1992. J. Am. Chem. Soc. 114, 9283.
      Lasky, L.A. 1992. Science 258, 964.