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855016 Rink Amide PEGA resin

Overview

Replacement Information

Key Spec Table

CAS #
58318-77-7

Pricing & Availability

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8550160001
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      Glass bottle 1 g
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      Description
      Catalogue Number855016
      Replaces01-64-0101
      Brand Family Novabiochem®
      Background InformationAn excellent acid-labile support for the solid phase synthesis of peptide amides. This resin is prepared by derivatization of amino PEGA resin with the modified Rink linker. It is supplied without Fmoc protection of the linker benzhydrylamine group as this has been found to improve stability. Cleavage is effected with 95% TFA.

      PEGA-based resins are compatible with aqueous and alcoholic solvents, and are permeable to macromolecules up to 35 kD.

      For further information, please refer to the product entry for amino PEGA resin (855015).

      Note: PEGA resins are supplied swollen in ethanol, with 1g dry resin corresponding to approximately 15 mL of swollen resin. As the beads of PEGA resins become very sticky and easily damaged when shrunk or dried, they are best handled in a swollen state. To use, the appropriate amount of swollen resin should be weighed into a reaction vessel and any residual ethanol removed by copious washings with the appropriate solvent or solvent mixture. After peptide assembly, the resin should be washed with DCM and transferred to the cleavage vessel. Excess DCM can be removed under vacuum, and the shrunk resin treated with the TFA cocktail.

      The characteristics of the swollen resin, its robustness and high permeability enables its use in both batch and continuous flow synthesis apparatus.

      The product number for this product was previously 01-64-0101.

      To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
      References
      Product Information
      CAS number58318-77-7
      HS Code3907 29 90
      Structure formula ImageStructure formula Image
      Quality LevelMQ200
      Applications
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Storage class10 - 13 Other liquids and solids
      WGKWGK 1 slightly hazardous to water
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      StorageStore at +2°C to +8°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Color (visual)white to yellow to beige
      Appearance of substance (visual)beads
      Loading (determined from the substitution of the Fmoc-Leu loaded resin)0.20 - 0.50 mmol/g
      Swelling Volume (in DMF)lot specific result
      dry resin %lot specific result
      The resin is sold swollen ethanol.
      Global Trade Item Number
      Catalogue Number GTIN
      8550160001 04027269109837