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MAB4388 Mouse Anti-Stella Antibody

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MAB4388
100 µg  
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      Overview

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MELISA, ICCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMAB4388
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionMouse Anti-Stella Antibody
      Background InformationStella is specifically expressed by oocytes, pluripotent cells and primordial germ cells at the time of their emergence in gastrulating embryos, and is an important maternal factor in the cleavage stages of mouse embryos (Bortvin, 2004). The requirement for stella in germ cell specification remains controversial, however, most embryos from stella deficient mice failed to develop normally and rarely reach the blastocyst stage (Bortvin, 2004; Payer, 2003). The stella gene encodes a protein with an SAP-like domain and splicing factor motif-like structure, suggesting possible roles in chromosomal organization and RNA processing (Payer, 2003).
      Product Information
      FormatPurified
      PresentationPurified Ascites presented as a liquid in 0.02M phosphate buffer, 0.25M NaCI, pH 7.6 with 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationMouse Anti-Stella Antibody detects level of Stella & has been published & validated for use in ELISA & IC.
      Key Applications
      • ELISA
      • Immunocytochemistry
      Biological Information
      Clone3H5.2
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityReacts with stella from human and mouse.
      IsotypeIgG1
      Species Reactivity
      • Human
      • Mouse
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes a protein that in mice may function as a maternal factor during the preimplantation stage of development. In mice, this gene may play a role in transcriptional repression, cell division, and maintenance of cell pluripotentiality. In humans, related intronless loci are located on chromosomes 14 and X.
      Gene Symbol
      • DPPA3
      • STELLAR
      • Stella
      • STELLA
      • stella
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q6W0C5 # May play a role in maintaining cell pluripotentiality.
      SIZE: 159 amino acids; 17851 Da
      SUBCELLULAR LOCATION: Nucleus (By similarity). Cytoplasm (By similarity).
      TISSUE SPECIFICITY: Low expression in testis, ovary and thymus. Expressed in embryonic stem and carcinoma cells. Highly expressed in testicular germ cell tumors.
      DEVELOPMENTAL STAGE: Expressed in fetal ovary.
      Stem Cell Type
      • Human Embryonic Stem Cells
      • Mouse Embryonic Stem Cells
      • Induced Pluripotent Stem Cells
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain refrigerated at 2-8C in undiluted aliquots for up to 12 months.
      Packaging Information
      Material Size100 µg
      Global Trade Item Number
      Catalogue Number GTIN
      MAB4388 04053252579837