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817058 Maleic acid

EMPROVE® ESSENTIAL Ph Eur,NF

Maleic acid MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: cis-Butenedioic acid

CAS #: 110-16-7 EC Number: 203-742-5 Molar Mass: 116.07 g/mol Chemical Formula: HOOCCH=CHCOOH Hill Formula: C₄H₄O₄ Grade: Ph Eur,NF
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Overview

Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
110-16-7203-742-5C₄H₄O₄HOOCCH=CHCOOH116.07 g/molPh Eur,NF

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      8170589025
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          Description
          Catalogue Number817058
          Synonymscis-Butenedioic acid
          DescriptionMaleic acid suitable for use as excipient
          Product Information
          CAS number110-16-7
          EC index number607-095-00-3
          EC number203-742-5
          GradePh Eur,NF
          Hill FormulaC₄H₄O₄
          Chemical formulaHOOCCH=CHCOOH
          Molar Mass116.07 g/mol
          HS Code2917 19 80
          Structure formula ImageStructure formula Image
          Quality LevelMQ500
          Physicochemical Information
          Density1.59 g/cm3 (20 °C)
          Melting Point130 - 135 °C
          pH value1.3 (100 g/l, H₂O, 20 °C)
          Vapor pressure<0.1 hPa (20 °C)
          Bulk density750 - 800 kg/m3
          Solubility478.8 g/l
          Toxicological Information
          LD 50 oralLD50 Rat 708 mg/kg
          LD 50 dermalLD50 Rabbit 1560 mg/kg
          Safety Information according to GHS
          Hazard Pictogram(s) Hazard Pictogram(s)
          Hazard Pictogram(s)
          Hazard Statement(s)H302 + H312: Harmful if swallowed or in contact with skin.
          H314: Causes severe skin burns and eye damage.
          H317: May cause an allergic skin reaction.
          H335: May cause respiratory irritation.
          Precautionary Statement(s)P260: Do not breathe dust.
          P271: Use only outdoors or in a well-ventilated area.
          P280: Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection.
          P301 + P312: IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.
          P303 + P361 + P353: IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water.
          P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
          Signal WordDanger
          RTECSOM9625000
          Storage class8A Combustible, corrosive hazardous materials
          WGKWGK 1 slightly hazardous to water
          Disposal3
          Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
          Safety Information
          Categories of dangerharmful, irritant, sensitizing
          Storage and Shipping Information
          StorageStore at +15°C to +25°C.
          Transport Information
          Declaration (railroad and road) ADR, RIDUN 3261 , 8, II
          Declaration (transport by air) IATA-DGRUN 3261 , 8, II
          Declaration (transport by sea) IMDG-CodeUN 3261 , 8, II, Segregation Group: 1 (Acids)
          Specifications
          Assay (calc.on anhydrous substance)99.0 - 101.0 %
          Assay (HPLC, calc. on anhydrous substance)98.0 - 102.0 %
          Identity (wet chemistry)passes test
          Identity (HPLC)passes test
          Identity (pH)passes test
          Identity (TLC)passes test
          Identity (IR)passes test
          Appearance of solutionpasses test
          Fe (Iron)≤ 5 ppm
          V (Vanadium)*≤ 1 ppm
          Fumaric acid (TLC)≤ 1.5 %
          Fumaric acid (HPLC)≤ 1.0 %
          Malic acid (HPLC)≤ 0.5 %
          Residual solvents (ICH Q3C)excluded by the production process
          Sulfated ash≤ 0.1 %
          Water (K. F.)≤ 0.5 %
          Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
          Corresponds to Ph Eur, NF
          Global Trade Item Number
          Catalogue Number GTIN
          8170581000 04022536548777
          8170589025 04022536648118