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422686 Kininogen, High Molecular Weight, Single Chain, Human Plasma - Calbiochem

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422686
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422686-1MG
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      Description
      OverviewNative, single chain, high molecular weight Kininogen from human plasma. Nonenzymatic cofactor of the contact activation system. Links prekallikrein to negatively charged surfaces, thereby allowing activation to kallikrein by surface-bound Factor α-XIIa. Also circulates in plasma in complex with Factor XI and may play a role in the activation of Factor XI to Factor XIa by Factor α-XIIa. Serves as a source of bradykinin, a potent vasoactive peptide important in hypotension studies.
      Catalogue Number422686
      Brand Family Calbiochem®
      References
      ReferencesWeisel, J.W., et al. 1994. J. Biol. Chem. 269, 10100.
      Product Information
      FormLiquid
      FormulationIn 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.
      Quality LevelMQ100
      Biological Information
      Purity≥95% by SDS-PAGE
      SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Concentration Label Please refer to vial label for lot-specific concentration
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Global Trade Item Number
      Catalogue Number GTIN
      422686-1MG 04055977187212