368055 Sigma-AldrichGranzyme B Inhibitor II - CAS 1258003-96-1 - Calbiochem
The Granzyme B Inhibitor II, also referenced under CAS 1258003-96-1, controls the biological activity of Granzyme B. This small molecule/inhibitor is primarily used for Cancer applications.
More>> The Granzyme B Inhibitor II, also referenced under CAS 1258003-96-1, controls the biological activity of Granzyme B. This small molecule/inhibitor is primarily used for Cancer applications. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: Caspase-8 Inhibitor I, Ac-IETD-CHO
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Overview
| Replacement Information |
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Key Spec Table
| CAS # | Empirical Formula |
|---|---|
| 1258003-96-1 | C₂₁H₃₄N₄O₁₀ |
Pricing & Availability
| Catalogue Number | Availability | Packaging | Qty/Pack | Price | Quantity | |
|---|---|---|---|---|---|---|
| 368055-1MG |
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Plastic ampoule | 1 mg |
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| References | |
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| References | Gao, C.F., et al. 2001. Exp. Cell. Res. 265, 145. Garcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608. Han, Z., et al. 1997. J. Biol. Chem. 272, 13422. |
| Product Information | |
|---|---|
| CAS number | 1258003-96-1 |
| ATP Competitive | N |
| Form | White lyophilized solid |
| Hill Formula | C₂₁H₃₄N₄O₁₀ |
| Chemical formula | C₂₁H₃₄N₄O₁₀ |
| Reversible | Y |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
|---|---|
| Primary Target | caspase-8 |
| Primary Target K<sub>i</sub> | 1 nM against caspase-8 |
| Purity | ≥95% by HPLC |
| Physicochemical Information | |
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| Cell permeable | N |
| Peptide Sequence | Ac-Ile-Glu-Thr-Asp-CHO |
| Dimensions |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information |
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| Product Usage Statements |
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| Packaging Information |
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| Transport Information |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
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| Catalogue Number | GTIN |
| 368055-1MG | 04055977192131 |
Documentation
Granzyme B Inhibitor II - CAS 1258003-96-1 - Calbiochem SDS
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Granzyme B Inhibitor II - CAS 1258003-96-1 - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 368055 |
References
| Reference overview |
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| Gao, C.F., et al. 2001. Exp. Cell. Res. 265, 145. Garcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608. Han, Z., et al. 1997. J. Biol. Chem. 272, 13422. |
Brochure
| Title |
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| Caspases and other Apoptosis Related Tools Brochure |