Millipore Sigma Vibrant Logo

361555 GSK-3 Inhibitor XIII - CAS 404828-08-6 - Calbiochem

The GSK-3 Inhibitor XIII, also referenced under CAS 404828-08-6, controls the biological activity of GSK-3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (5-Methyl-1H-pyrazol-3-yl)-(2-phenylquinazolin-4-yl)amine

Primary Target: GSK-3
View Products on Sigmaaldrich.com
361555
View Pricing & Availability

Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
404828-08-6C₁₈H₁₅N₅

Pricing & Availability

Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
361555-1MG
Retrieving availability...
—
Limited Availability Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      		 Plastic ampoule 1 mg
      Retrieving price...
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
       
      —
      Request Pricing
      		 —
      361555-5MG
      Retrieving availability...
      —
      Limited Availability Limited Availability
      In Stock 
      Discontinued
      Limited Quantities Available
      Availability to be confirmed
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          		 Plastic ampoule 5 mg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity is a multiple of
          Maximum Quantity is
          Upon Order Completion More Information
          You Saved ()
           
          —
          Request Pricing
          		 —
          Description
          OverviewAn aminopyrazole compound that acts as a potent and ATP-binding site inhibitor of GSK-3 with a Ki of 24 nM.
          Catalogue Number361555
          Brand Family Calbiochem®
          Synonyms(5-Methyl-1H-pyrazol-3-yl)-(2-phenylquinazolin-4-yl)amine
          References
          ReferencesPierce, A.C., et al. 2005. J. Med. Chem. 48, 1278.
          Product Information
          CAS number404828-08-6
          ATP CompetitiveN
          FormWhite solid
          Hill FormulaC₁₈H₁₅N₅
          Chemical formulaC₁₈H₁₅N₅
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetGSK-3
          Primary Target K<sub>i</sub>24 nM against GSK-3
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Carcinogenic / Teratogenic
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Catalogue Number GTIN
          361555-1MG 04055977214147
          361555-5MG 04055977214154

          Documentation

          Required Licenses

          Title
          CARTA DE USO GENERAL 2016
          PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

          GSK-3 Inhibitor XIII - CAS 404828-08-6 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          GSK-3 Inhibitor XIII - CAS 404828-08-6 - Calbiochem Certificates of Analysis

          TitleLot Number
          361555

          References

          Reference overview
          Pierce, A.C., et al. 2005. J. Med. Chem. 48, 1278.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision01-July-2008 RFH
          Synonyms(5-Methyl-1H-pyrazol-3-yl)-(2-phenylquinazolin-4-yl)amine
          DescriptionA potent and ATP-competitive inhibitor of GSK-3 (Ki = 24 nM).
          FormWhite solid
          CAS number404828-08-6
          Chemical formulaC₁₈H₁₅N₅
          Structure formulaStructure formula
          Purity≥95% by HPLC
          SolubilityDMSO (5 mg/ml)
          Storage Protect from light
          +2°C to +8°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Toxicity Carcinogenic / Teratogenic
          ReferencesPierce, A.C., et al. 2005. J. Med. Chem. 48, 1278.