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559400 SB 203580, Iodo- - CAS 189319-35-5 - Calbiochem

A highly specific, cell-permeable, reversible, ATP-competitive, and potent inhibitor of p38 MAP kinase.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: 4-(3-Iodophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole, p38 MAP Kinase Inhibitor XIII

Primary Target: p38 MAP kinase
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      Aperçu

      Replacement Information

      Tableau de caractéristiques principal

      CAS #Empirical Formula
      189319-35-5C₂₁H₁₆IN₃OS
      Description
      Overview

      This product has been discontinued.



      A highly specific, cell-permeable, reversible, ATP-competitive, and potent inhibitor of p38 MAP kinase. Exhibits similar inhibitory potency as its parent compound SB 203580 (Cat. No. 559389). Useful for the identification of inhibitor binding sites in p38 MAP kinase.
      Catalogue Number559400
      Brand Family Calbiochem®
      Synonyms4-(3-Iodophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole, p38 MAP Kinase Inhibitor XIII
      References
      ReferencesTong, L., et al. 1997. Nat. Struct. Biol. 4, 311.
      Product Information
      CAS number189319-35-5
      ATP CompetitiveY
      FormOff-white solid
      Hill FormulaC₂₁H₁₆IN₃OS
      Chemical formulaC₂₁H₁₆IN₃OS
      ReversibleY
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Primary Targetp38 MAP kinase
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      559400 0

      Documentation

      SB 203580, Iodo- - CAS 189319-35-5 - Calbiochem Certificats d'analyse

      TitreNuméro de lot
      559400

      Références bibliographiques

      Aperçu de la référence bibliographique
      Tong, L., et al. 1997. Nat. Struct. Biol. 4, 311.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision19-April-2011 RFH
      Synonyms4-(3-Iodophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole, p38 MAP Kinase Inhibitor XIII
      DescriptionA highly specific, cell-permeable, reversible, ATP-competitive, and potent inhibitor of p38 MAP kinase, similar to SB 203580 (Cat. No. 559389). Useful for the identification of inhibitor binding sites of the p38 MAP kinase enzyme.
      FormOff-white solid
      CAS number189319-35-5
      Chemical formulaC₂₁H₁₆IN₃OS
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (5 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesTong, L., et al. 1997. Nat. Struct. Biol. 4, 311.

      Produits & Applications associés

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      Catégories

      Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Protein Phosphorylation / Dephosphorylation > MAP Kinase Inhibitors