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AB10200-25UG Rb X Bovine Perilipin A

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AB10200-25UG
25 μg  
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      Tableau de caractéristiques principal

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      B, MWBRbPurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB10200-25UG
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionRb X Bovine Perilipin A
      Background InformationPerilipin A is the predominant isoform of perilipins a family of proteins which are the most abundant proteins at the surfaces of lipid droplets in adipocytes and are also found in steroidogenic cells.
      References
      Product Information
      FormatPurified
      PresentationPurified immunoglobulin presented as a liquid in 0.02M Phosphate buffer,0.25M NaCl,0.1% Sodium Azide, pH 7.6
      Quality LevelMQ100
      Applications
      ApplicationDetect Perilipin A using this Anti-Perilipin A Antibody validated for use in WB.
      Key Applications
      • Western Blotting
      Application NotesSuggested dilutions:
      Western Blot: 0.1-0.2 μg/mL
      Biological Information
      ImmunogenBovine Perilipin A
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Bovine
      • Mouse
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis.
      Gene Symbol
      • PLIN
      • PERI
      • Perilipin
      • perilipin
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: O60240 # Modulator of adipocyte lipid metabolism, it coats lipid storage droplets to protect them to be broken down by hormone- sensitive lipase (HSL). Its absence may result in leanness.
      SIZE: 522 amino acids; 55950 Da
      SUBUNIT: Interacts with ABHD5 (By similarity).
      SUBCELLULAR LOCATION: Lipid droplet (By similarity). Note=Lipid droplet surface-associated (By similarity).
      TISSUE SPECIFICITY: Adipocytes.
      PTM: Major cAMP-dependent protein kinase-substrate in adipocytes, also dephosphorylated by PP1. When phosphorylated, may be maximally sensitive to HSL and when unphosphorylated, may play a role in the inhibition of lipolysis, by acting as a barrier in lipid droplet (By similarity).
      SIMILARITY: SwissProt: O60240 ## Belongs to the perilipin family.
      Molecular Weight64kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by immunoblot.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain frozen at -20C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze-thaw cycles.
      Packaging Information
      Material Size25 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      AB10200-25UG 04054839350269

      Documentation