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14-592M PTPMEG-2 Protein, 250 µg

N-terminal GST-tagged, recombinant human PTP-MEG2, amino acid residues 283-end. For use in Phosphatase Assays.

14-592M
250 µg  Also available in 10 μg size (cat#14-592) and in bulk (cat# 14-592-K).
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      Replacement Information
      Description
      Catalogue Number14-592M
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionPTPMEG-2 Protein, 250 µg
      OverviewN-terminal GST-tagged, recombinant human PTP-MEG2, amino acid residues 283-end.
      References
      Product Information
      Quality LevelMQ300
      Applications
      ApplicationN-terminal GST-tagged, recombinant human PTP-MEG2, amino acid residues 283-end. For use in Phosphatase Assays.
      Key Applications
      • Phosphatase Assay
      Biological Information
      SourceExpressed in E. coli
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis.
      Gene Symbol
      • PTPN9
      • PTPase-MEG2
      • MEG2
      Protein TargetPTPMEG-2
      Purification MethodGlutathione-agarose
      Target Sub-FamilyTyr phosphatase
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P43378 # Protein-tyrosine phosphatase that could participate in the transfer of hydrophobic ligands or in functions of the Golgi apparatus.
      SIZE: 593 amino acids; 68020 Da
      SUBCELLULAR LOCATION: Cytoplasm (Probable).
      SIMILARITY: SwissProt: P43378 ## Belongs to the protein-tyrosine phosphatase family. Non-receptor class 3 subfamily. & Contains 1 CRAL-TRIO domain. & Contains 1 tyrosine-protein phosphatase domain.
      Molecular Weight62.5kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by dephosphorylation of 100μM DiFMUP
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10 μg size (cat#14-592) and in bulk (cat# 14-592-K).
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      14-592M 04053252586101

      Documentation

      Produits & Applications associés

      Alternative Packsize

      Référence Description  
      14-592 PTPMEG-2 Protein, 10 µg Prix & Disponibilité

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      Catégories

      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Phosphatases
      Life Science Research > Proteins and Enzymes > Purified Phosphatases