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TGFBMAG-64K-01BK MILLIPLEX MAP TGFß1 Magnetic Bead Single Plex Kit Space Saver (Bulk) Packaging

This MILLIPLEX MAP TGF ß1 (Transforming Growth Factor Beta) - Single Plex is an Immunology Multiplex Assay used for the simultaneous quantification of theTGF-β1 biomarker in the following species: Mou

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Key Applications: Multiplexing Detection Methods: Luminex xMAP Research Category: Inflammation & Immunology
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TGFBMAG-64K-01BK
96-well plate  
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      Aperçu

      Tableau de caractéristiques principal

      Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
      TGF-β1 H, M, R, NhP, Ca, Fe, PoMplexLuminex xMAP
      Description
      Catalogue NumberTGFBMAG-64K-01BK
      Trade Name
      • MILLIPLEX
      DescriptionMILLIPLEX MAP TGFß1 Magnetic Bead Single Plex Kit Space Saver (Bulk) Packaging
      Background InformationThe transforming growth factor beta (TGFβ) system, a superfamily of cytokines as well as signaling pathways, is highly conserved throughout the animal kingdom. TGFβ functions in immune cell development, angiogenesis, wound healing and embryonic development, bone development and plays a critical role in immune response, heart disease, and cancer. In its normal state TGFβ is one of the few classes of proteins able to inhibit cell growth by halting mitosis at the G1 state, inducing cell differentiation or apoptosis. However, during oncogenesis mutations in the TGFβ signaling pathway result in tumor cell resistance to the effects of normally functioning TGFβ, causing proliferation without regulation. Initial research suggests that VE-cadherin may enhance the mutated TGFβ signaling pathway.
      Product Information
      Detection methodLuminex xMAP
      HS Code3822 19 90
      ConfigurationSingle Plex
      Precision, %
      • Inter-assay: < 10
      • Intra-assay: < 10
      Panel TypeMAGNETIC Cytokines/Chemokines
      Quality LevelMQ200
      Applications
      ApplicationThis MILLIPLEX MAP TGF ß1 (Transforming Growth Factor Beta) - Single Plex is an Immunology Multiplex Assay used for the simultaneous quantification of theTGF-β1 biomarker in the following species: Mouse/Human/Rat/Pig/Horse/Rabbit/Guinea Pig/Hamster.
      Key Applications
      • Multiplexing
      Application Notes• This assay requires an acidification sample treatment.
      • This is a 2-hour or overnight incubation assay.
      • This assay requires 25 μL of a 1:30 dilution after treatment of serum and plasma samples.
      Biological Information
      SpecificityIn addition to human TGFβ1, the assay can detect TGFβ1 in serum of the following; horse, rabbit, mouse, rat, mini pig, canine, hamster, guinea pig, rhesus monkey and cynomolgous monkey. However, the exact amount of cross reactivity has not been determined.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      • Non-human Primate
      • Canine
      • Feline
      • Pig
      Analytes Available
      • TGF-β1
      Physicochemical Information
      Sensitivity
      • 12 pg/mL
      Standard Curve Range
      • 9.8 - 2,500 pg/mL
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsRecommended storage for kit components is 2 - 8°C.
      Packaging Information
      Material Size96-well plate
      Global Trade Item Number
      Référence GTIN
      TGFBMAG-64K-01BK 04055977114317