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371543 Guanosine 5ʹ-O-(2-Thiodiphosphate), Trilithium Salt - CAS 97952-36-8 - Calbiochem

Non-hydrolyzable GDP analog that competitively inhibits G-protein activation by GTP and GTP analogs. Stimulates adenylate cyclase activity in sarcolemmal membranes by inactivating Gi proteins.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: GDP-β-S, 3Li

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      Aperçu

      Replacement Information

      Tableau de caractéristiques principal

      CAS #Empirical Formula
      97952-36-8C₁₀H₁₂N₅O₁₀P₂S . 3Li
      Description
      OverviewNon-hydrolyzable GDP analog that competitively inhibits G-protein activation by GTP and GTP analogs. Stimulates adenylate cyclase activity in sarcolemmal membranes by inactivating Gi proteins.
      Catalogue Number371543
      Brand Family Calbiochem®
      SynonymsGDP-β-S, 3Li
      References
      ReferencesPiacentini, L., et al. 1996. Biochim. Biophys. Acta 1282, 11.
      Eberhard, D.A. and Holz, R.W., et al. 1991. Biochem J. 279, 447.
      Silk, S.T., et al. 1989. J. Biol. Chem. 264, 21466.
      Burch, R.M., et al. 1987. Proc. Natl. Acad. Sci. USA 84, 6374.
      Gilman, A.G. 1987. Annu. Rev. Biochem. 56, 615.
      Eckstein, F., et al. 1979. J. Biol. Chem. 254, 9829.
      Product Information
      CAS number97952-36-8
      FormWhite solid
      Hill FormulaC₁₀H₁₂N₅O₁₀P₂S . 3Li
      Chemical formulaC₁₀H₁₂N₅O₁₀P₂S . 3Li
      Hygroscopic Hygroscopic
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥85% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions lose 5% of their activity after 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      371543 0

      Documentation

      Guanosine 5ʹ-O-(2-Thiodiphosphate), Trilithium Salt - CAS 97952-36-8 - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Guanosine 5ʹ-O-(2-Thiodiphosphate), Trilithium Salt - CAS 97952-36-8 - Calbiochem Certificats d'analyse

      TitreNuméro de lot
      371543

      Références bibliographiques

      Aperçu de la référence bibliographique
      Piacentini, L., et al. 1996. Biochim. Biophys. Acta 1282, 11.
      Eberhard, D.A. and Holz, R.W., et al. 1991. Biochem J. 279, 447.
      Silk, S.T., et al. 1989. J. Biol. Chem. 264, 21466.
      Burch, R.M., et al. 1987. Proc. Natl. Acad. Sci. USA 84, 6374.
      Gilman, A.G. 1987. Annu. Rev. Biochem. 56, 615.
      Eckstein, F., et al. 1979. J. Biol. Chem. 254, 9829.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision07-July-2008 RFH
      SynonymsGDP-β-S, 3Li
      DescriptionA nonhydrolyzable GDP analog that competitively inhibits G-protein activation by GTP and GTP analogs.
      FormWhite solid
      CAS number97952-36-8
      Chemical formulaC₁₀H₁₂N₅O₁₀P₂S . 3Li
      Structure formulaStructure formula
      Purity≥85% by HPLC
      SolubilityH₂O (50 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions lose 5% of their activity after 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesPiacentini, L., et al. 1996. Biochim. Biophys. Acta 1282, 11.
      Eberhard, D.A. and Holz, R.W., et al. 1991. Biochem J. 279, 447.
      Silk, S.T., et al. 1989. J. Biol. Chem. 264, 21466.
      Burch, R.M., et al. 1987. Proc. Natl. Acad. Sci. USA 84, 6374.
      Gilman, A.G. 1987. Annu. Rev. Biochem. 56, 615.
      Eckstein, F., et al. 1979. J. Biol. Chem. 254, 9829.