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218725 Caspase-5, Human, Recombinant, E. coli

Caspase-5, Human, Recombinant, is expressed in E. coli. It is an inflammatory caspase.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: ICErel-III, TY

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218725
  
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      Aperçu

      Replacement Information
      Description
      OverviewRecombinant, human caspase-5 expressed in E. coli. Suitable for the study of enzyme regulation and kinetics, target substrate cleavage, and inhibitor screening. MW: 10000 and 22000.
      M.W. 10,000 and 22,000 (heterodimer).
      Catalogue Number218725
      Brand Family Calbiochem®
      SynonymsICErel-III, TY
      References
      ReferencesSchwartz, S. et al. 1999. Cancer Res. 59, 2995.
      Fucheu, C., et al. 1996. Eur. J. Biochem. 236, 207.
      Munday, N.A., et al. 1995. J. Biol. Chem. 270, 15870.
      Product Information
      Unit of DefinitionOne unit is defined as the amount of enzyme that will cleave 1.0 pmol substrate Ac-LEHD-<i>p</i>NA (<a href="http://www.emdbiosciences.com/products/EMD_BIO-218805">Cat. No. 218805</a>) per min at 25°C, pH 7.4.
      FormLiquid
      FormulationIn 100 mM NaCl, 50 mM HEPES, 10 mM DTT, 1 mM EDTA, 10% glycerol, 0.5% CHAPS, pH 7.4.
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥80% by SDS-PAGE
      Specific Activity≥100,000 units/mg protein
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsAfter initial defrost, aliquot and freeze at -70°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      218725 0

      Documentation

      Caspase-5, Human, Recombinant, E. coli FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Caspase-5, Human, Recombinant, E. coli Certificats d'analyse

      TitreNuméro de lot
      218725

      Références bibliographiques

      Aperçu de la référence bibliographique
      Schwartz, S. et al. 1999. Cancer Res. 59, 2995.
      Fucheu, C., et al. 1996. Eur. J. Biochem. 236, 207.
      Munday, N.A., et al. 1995. J. Biol. Chem. 270, 15870.

      Brochure

      Titre
      Caspases and other Apoptosis Related Tools Brochure
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision04-June-2008 RFH
      SynonymsICErel-III, TY
      DescriptionRecombinant, human caspase-5 expressed in E. coli. A member of the caspase-1 subfamily of cysteine proteases involved in Fas-mediated apoptosis. Caspase-5 cleavage site is reported to be Asp311 and Asp330. May also cleave at Asp121. Suitable for the study of enzyme regulation and kinetics, target substrate cleavage, and inhibitor screening. MW: 10000 and 22000.
      FormLiquid
      FormulationIn 100 mM NaCl, 50 mM HEPES, 10 mM DTT, 1 mM EDTA, 10% glycerol, 0.5% CHAPS, pH 7.4.
      Purity≥80% by SDS-PAGE
      Specific activity≥100,000 units/mg protein
      Unit definitionOne unit is defined as the amount of enzyme that will cleave 1.0 pmol substrate Ac-LEHD-pNA (Cat. No. 218805) per min at 25°C, pH 7.4.
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsAfter initial defrost, aliquot and freeze at -70°C.
      Toxicity Standard Handling
      ReferencesSchwartz, S. et al. 1999. Cancer Res. 59, 2995.
      Fucheu, C., et al. 1996. Eur. J. Biochem. 236, 207.
      Munday, N.A., et al. 1995. J. Biol. Chem. 270, 15870.