Millipore Sigma Vibrant Logo

GF136 BAFF Protein, Recombinant human

The Human BAFF protein (B-cell activating factor belonging to the TNF family) is a novel ligand in the TNF family.

BAFF Protein, Recombinant human : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Key Applications: Cell Culture, Stem Cell Culture UniProt Number: Q9Y275 Entrez Gene Number: NM_006573.3
View Products on Sigmaaldrich.com
GF136
20 µg  
Prix en cours de récupération
Le prix n'a pas pu être récupéré
La quantité minimale doit être un multiple de
Maximum Quantity is
À la validation de la commande Plus d'informations
Vous avez sauvegardé ()
 
—
Demander le prix
—
Disponibilité limitée Disponibilité limitée
En stock 
Interrompu(e)
Disponible en quantités limitées
Disponibilité à confirmer
    Pour le restant : Nous vous tiendrons informé
      Pour le restant : Nous vous tiendrons informé
      Nous vous tiendrons informé
      Contacter le Service Clients
      Contact Customer Service

       

      Contacter le Service Clients

      Aperçu

      Replacement Information

      Tableau de caractéristiques principal

      Key ApplicationsSpeciesSourcePurity
      CULT, CultHuman E.coliGreater than 98% by SDS-PAGE. Endotoxin level is less than 0.1 ng per μg (1 EU/ug) of BAFF.
      Description
      Catalogue NumberGF136
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionBAFF Protein, Recombinant human
      OverviewHuman BAFF (B-cell activating factor belonging to the TNF family) is a novel ligand in the TNF family. BAFF plays an important role as co-stimulator of B-cell proliferation and function. Recombinant human BAFF is a soluble 17.0 kDa protein containing 153 amino acid residues, comprising the TNF-like extracellular domain of BAFF.
      Alternate Names
      • B-cell Activation Factor
      • TALL-1
      • THANK
      • BLyS
      References
      Product Information
      PresentationLyophilized from sterile filtered 0.5X PBS, pH 7.5, and 0.5 mM DTT, containing no additives.
      Quality LevelMQ100
      Applications
      ApplicationThe Human BAFF protein (B-cell activating factor belonging to the TNF family) is a novel ligand in the TNF family.
      Key Applications
      • Cell Culture
      • Stem Cell Culture
      Biological Information
      PurityGreater than 98% by SDS-PAGE. Endotoxin level is less than 0.1 ng per μg (1 EU/ug) of BAFF.
      SourceE.coli
      Specific ActivityHuman BAFF is biologically active when compared to standards. The ED50 as determined by its dose-dependent mitogenic activity on human RPMI 8226 cells is 5-10 ng/mL.
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells.
      Gene Symbol
      • TNFSF13B
      • BLyS
      • TNFSF20
      • CD257
      • BAFF
      • TALL1
      • DTL
      • TALL-1
      • ZTNF4
      • THANK
      • BLYS
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q9Y275 # Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.
      SIZE: 285 amino acids; 31223 Da
      SUBUNIT: Homotrimer.
      SUBCELLULAR LOCATION: Cell membrane; Single-pass type II membrane protein. & Tumor necrosis factor ligand superfamily member 13b, soluble form: Secreted.
      TISSUE SPECIFICITY: Abundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bone marrow, T- cells and dendritic cells. A lower expression seen in placenta, heart, lung, fetal liver, thymus, and pancreas.
      PTM: The soluble form derives from the membrane form by proteolytic processing. & N-glycosylated.
      SIMILARITY: SwissProt: Q9Y275 ## Belongs to the tumor necrosis factor family.
      Stem Cell Type
      • Human Embryonic Stem Cells
      • Induced Pluripotent Stem Cells
      Molecular Weight17.0 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsThe lyophilized powder is stable for a few weeks at room temperature, but best stored at -20°C for up to one year from date of receipt. Reconstituted material can be stored at 2°-8°C for one week, but undiluted aliquots at -20°C are recommended. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size20 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      GF136 04053252625329

      Documentation

      BAFF Protein, Recombinant human FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      BAFF Protein, Recombinant human Certificats d'analyse

      TitreNuméro de lot
      BAFF, HUMAN RECOMBINANT PROTEIN 2978900
      BAFF, HUMAN RECOMBINANT PROTEIN 3125609
      BAFF, HUMAN RECOMBINANT PROTEIN 3019893
      BAFF, HUMAN RECOMBINANT PROTEIN 3058630
      BAFF, HUMAN RECOMBINANT PROTEIN - 2031374 2031374
      BAFF, HUMAN RECOMBINANT PROTEIN - 3734131 3734131
      BAFF, HUMAN RECOMBINANT PROTEIN - 4031024 4031024
      BAFF, HUMAN RECOMBINANT PROTEIN - DAM1576845 DAM1576845
      BAFF, HUMAN RECOMBINANT PROTEIN - DAM1612128 DAM1612128
      BAFF, HUMAN RECOMBINANT PROTEIN - JBC1889919 JBC1889919
      Show more

      Fiche technique

      Titre
      BAFF, HUMAN RECOMBINANT PROTEIN

      Newsletters / Publications

      Title
      Cellutions Newsletter: 2007, Volume 1
      Cellutions Newsletter: 2008, Volume 1
      Cellutions Newsletter: 2008, Volume 3

      Produits & Applications associés

      Familles de produits

      Cytokines and Growth Factors

      EMD Millipore offers a comprehensive range of highly purified bioactive cytokines and growth factors for use in human, mouse, and rat cell culture, stem cell differentiation and ELISA studies.
      En savoir plus >>

      Catégories

      Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
      Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors