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AB3258 Anti-Puromycin Sensitive Aminopeptidase Antibody

This Anti-Puromycin Sensitive Aminopeptidase Antibody is validated for use in WB, IC for the detection of Puromycin Sensitive Aminopeptidase.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Research Category: Metabolism Research Sub-Category: Enzymes & Biochemistry Gene Symbol: NPEPPS, MP100, PSA, EC 3.4.11.- UniProt Number: P55786
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AB3258
50 µL  
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      Tableau de caractéristiques principal

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, RWB, ICCGtPurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB3258
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Puromycin Sensitive Aminopeptidase Antibody
      References
      Product Information
      FormatPurified
      PresentationPurified immunoglobulin. Liquid in phosphate buffered saline.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Puromycin Sensitive Aminopeptidase Antibody is validated for use in WB, IC for the detection of Puromycin Sensitive Aminopeptidase.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      Application NotesWestern blot: 1:1,000

      Immunocytochemistry: 1:1,000

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenRat puromycin sensitive aminopeptidase.
      HostGoat
      SpecificityRecognizes puromycin sensitive aminopeptidase.

      SPECIES REACTIVITIES: It is expected that the antibody may react with other species. Reactivity with other species has not been confirmed.
      Species Reactivity
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. This enzyme degrades enkaphalins in the brain, and studies in mouse suggest that it is involved in proteolytic events regulating the cell cycle.
      Gene Symbol
      • NPEPPS
      • MP100
      • PSA
      • EC 3.4.11.-
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P55786 # Aminopeptidase with broad substrate specificity to several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity (By similarity).
      COFACTOR: Binds 1 zinc ion per subunit (By similarity).
      SIZE: 919 amino acids; 103276 Da
      SUBCELLULAR LOCATION: Cytoplasm (Potential). Nucleus (Potential).
      SIMILARITY: SwissProt: P55786 ## Belongs to the peptidase M1 family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

      During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container's cap.
      Packaging Information
      Material Size50 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      AB3258 04053252282928

      Documentation

      Anti-Puromycin Sensitive Aminopeptidase Antibody FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Anti-Puromycin Sensitive Aminopeptidase Antibody Certificats d'analyse

      TitreNuméro de lot
      GOAT ANTI-PUROMYCIN SENSITIVE AMINOPEPTIDASE 3073338
      GOAT ANTI-PUROMYCIN SENSITIVE AMINOPEPTIDASE POLYCLONAL ANTIBODY - 2383057 2383057
      GOAT ANTI-PUROMYCIN SENSITIVE AMINOPEPTIDASE POLYCLONAL ANTIBODY - 2446734 2446734
      GOAT ANTI-PUROMYCIN SENSITIVE AMINOPEPTIDASE - 3266811 3266811
      GOAT ANTI-PUROMYCIN SENSITIVE AMINOPEPTIDASE - 3547785 3547785
      GOAT ANTI-PUROMYCIN SENSITIVE AMINOPEPTIDASE - 3795238 3795238
      GOAT ANTI-PUROMYCIN SENSITIVE AMINOPEPTIDASE - 3939230 3939230

      Références bibliographiques

      Aperçu de la référence bibliographiqueNº PubMed
      Degradation of tau protein by puromycin-sensitive aminopeptidase in vitro
      Sengupta, Soma, et al.
      Biochemistry, 45:15111-15119 (2006)  2005

      		17154549 17154549
      Studies on the tissue distribution of the puromycin-sensitive enkephalin-degrading aminopeptidases
      McLellan, S, et al.
      J. Neurochem., 51:1552-1559 (1988)  1987

      		3171591 3171591