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ABC143 Anti-PEX13 (peroxisomal membrane marker) Antibody

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ABC143
100 µL  
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      Tableau de caractéristiques principal

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWBRbSerumPolyclonal Antibody
      Description
      Catalogue NumberABC143
      DescriptionAnti-PEX13 (peroxisomal membrane marker) Antibody
      Alternate Names
      • Peroxisomal membrane protein PEX13
      • Peroxin-13
      Background InformationPeroxisomal membrane protein 13 (PEX13) is a component of the peroxisomal translocation machinery, which binds to peroxisomal targeting signal receptors via its SH3 domain, and facilitates the import of these receptors into the peroxisome membrane. Defects in PEX13 have been linked to neurodegenerative disorders, such as Zellweger syndrome.
      References
      Product Information
      FormatSerum
      Control
      • HepG2 cell lysate
      PresentationRabbit polyclonal serum with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-PEX13 (peroxisomal membrane marker) Antibody is validated for use in Western Blotting, ICC for the detection of PEX13 (peroxisomal membrane marker).
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenRecombinant protein corresponding to human PEX13 (peroxisomal membrane marker 13).
      HostRabbit
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • PEX13
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~49 kDa observed. This protein has an expected molecular weight of 44 kDa; however, it has been observed at ~49 kDa (Muller, C. C., et al. 2011. Dis Model Mech. 4(1):104-110.). An uncharacterized band may be observed at ~41 kDa in some cell lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in HepG2 cell lysate.

      Western Blot Analysis: A 1:1,000 dilution of this antibody detected PEX13 (peroxisomal membrane marker) in HepG2 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      ABC143 04053252599651

      Documentation

      Anti-PEX13 (peroxisomal membrane marker) Antibody FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Anti-PEX13 (peroxisomal membrane marker) Antibody Certificats d'analyse

      TitreNuméro de lot
      Anti-PEX13 (peroxisomal membrane -2707195 2707195
      Anti-PEX13 (peroxisomal membrane marker) - 2536844 2536844
      Anti-PEX13 (peroxisomal membrane marker) - 3207648 3207648
      Anti-PEX13 (peroxisomal membrane marker) - 3698185 3698185
      Anti-PEX13 (peroxisomal membrane marker) - 3852296 3852296
      Anti-PEX13 (peroxisomal membrane marker) - 4123906 4123906
      Anti-PEX13 (peroxisomal membrane marker) - Q2050305 Q2050305
      Anti-PEX13 (peroxisomal membrane marker) Polyclonal Antibody 3031610
      Anti-PEX13 (peroxisomal membrane marker) Polyclonal Antibody 2909533

      Références bibliographiques

      Aperçu de la référence bibliographiqueNº PubMed
      A PEX7-centered perspective on the peroxisomal targeting signal type 2-mediated protein import pathway.
      Rodrigues, TA; Alencastre, IS; Francisco, T; Brites, P; Fransen, M; Grou, CP; Azevedo, JE
      Molecular and cellular biology  34  2917-28  2014

      Afficher le résumé
      24865970 24865970
      Human pex19p binds peroxisomal integral membrane proteins at regions distinct from their sorting sequences.
      Fransen, M, et al.
      Mol. Cell. Biol., 21: 4413-24 (2001)  2001

      Afficher le résumé
      11390669 11390669

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      Catégories

      Life Science Research > Antibodies and Assays > Primary Antibodies