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CBL1337F Anti-PECAM-1 Antibody, clone 390, FITC conjugated

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CBL1337F
500 µg  
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      Tableau de caractéristiques principal

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MFC, IHCRFITCMonoclonal Antibody
      Description
      Catalogue NumberCBL1337F
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-PECAM-1 Antibody, clone 390, FITC conjugated
      Alternate Names
      • CD31
      Background InformationPECAM-1 is a type I integral membrane glycoprotein, and a member of the immunoglobulin superfamily of cell surface receptors. PECAM-1 is constitutively expressed on the surface of endothelial cells where it is concentrated at cell junctions. PECAM-1 is also expressed at low levels on all leukocytes and platelets. Homotypic interaction of CD31 is important in cell-cell interaction, cell-matrix interaction and signal transduction.
      Product Information
      FormatFITC
      PresentationPurified immunoglobulin conjugated to fluorescein. Liquid in in phosphate buffered saline containing 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-PECAM-1 Antibody, clone 390, FITC conjugated is validated for use in FC, IH for the detection of PECAM-1.
      Key Applications
      • Flow Cytometry
      • Immunohistochemistry
      Application NotesFlow Cytometry: = 1 μg per 10e6 cells in 100 μL volume

      Immunohistochemistry: acteone fixed frozen tissue sections.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenMouse leukocyte cell line 32D
      Clone390
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRat
      SpecificityCBL1337 recognizes mouse PECAM-1, a 130-140 kDa type 1 integral membrane glycoprotein. This antibody has been shown to inhibit the aggregation of L cells transfected with a variant form of PECAM-1 (DeLisser, 1993).
      IsotypeIgG2aκ
      Species Reactivity
      • Mouse
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • PECAM1
      • EndoCAM
      • GPIIA
      • PECAM-1
      • CD31
      • CD31/EndoCAM
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P16284 # This protein is a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions.
      SIZE: 738 amino acids; 82536 Da
      SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
      TISSUE SPECIFICITY: Long isoform predominates all tissues examined, isoform Delta12 was detected only in trachea and isoform Delta14-15 only in lung, isoform Delta14 was detected in all tissues examined with the strongest expression in heart.
      PTM: Phosphorylated on Ser and Tyr residues after cellular activation.
      SIMILARITY: SwissProt: P16284 ## Contains 6 Ig-like C2-type (immunoglobulin-like) domains.
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at 2°-8°C for up to 12 months from date of receipt. DO NOT FREEZE.
      Packaging Information
      Material Size500 µg
      Global Trade Item Number
      Référence GTIN
      CBL1337F 04053252278334