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ABE577 Anti-Myb Binding Protein 1A Antibody

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ABE577
100 µL  
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      Tableau de caractéristiques principal

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, ICC, ChIPRbSerumPolyclonal Antibody
      Description
      Catalogue NumberABE577
      DescriptionAnti-Myb Binding Protein 1A Antibody
      Alternate Names
      • Myb-binding protein 1A
      Background InformationMyb-binding protein 1A (MYBBP1A) interacts with sequence specific DNA-binding proteins in order to activate or repress transcription. Transcriptional repression via Myb-binding protein 1A is thought to be mediated by histone deacetylase activity (HDAC activity).
      Product Information
      FormatSerum
      Control
      • A431 cell lysate
      PresentationRabbit polyclonal serum with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Myb Binding Protein 1A Antibody is a highly specific rabbit polyclonal antibody, that targets Myb-binding protein 1A & has been tested in western blotting & ICC.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      • Chromatin Immunoprecipitation (ChIP)
      Application NotesImmunocytochemistry Analysis: A 1:500 dilution from a representative lot detected Myb Binding Protein 1A in diploid human lung embryonic fibroblasts (Prof. Atilla Nemeth, University of Regensburg, Germany.).

      Immunocytochemistry Analysis: A representative lot from an independent laboratory detected Myb Binding Protein 1A in HeLa cells (Hochstatter, J., et al. (2012). J Biol Chem. 287(29):24365-24377.).

      Chromatin Immunoprecipitation (ChIP) Analysis: A representative lot from an independent laboratory immunoprecipitated Myb Binding Protein 1A in ChIP (Hochstatter, J., et al. (2012). J Biol Chem. 287(29):24365-24377.).
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human Myb Binding Protein 1A.
      HostRabbit
      SpecificityThis antibody detects the full length and cleaved forms of Myb Binding Protein 1A.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • MYBBP1A
      • P160
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~160 kDa observed. Uncharacterized band(s) may be observed in some cell lysates. The full length of this protein is observed at ~160 kDa; however, it is proteolytically cleaved into ~140 kDa and ~67 kDa fragments (Hochstatter, J., et al. (2012). J Biol Chem. 287(29):24365-24377.; Mori, S., et al. (2012). PLoS One. 7(10):e39723.).
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in A431 cell lysate.

      Western Blotting Analyis: A 1:1,000 dilution from a representative lot detected Myb Binding Protein 1A in 10 µg of A431 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Global Trade Item Number
      Référence GTIN
      ABE577 04053252913952