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MABF1555 Anti-CD80 (mouse), APC, clone 16-10A1 Antibody

This Anti-CD80 (mouse), APC, clone 16-10A1 Antibody is validated for use in Flow Cytometry for the detection of CD80.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: Cd80, B7 UniProt Number: Q00609
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MABF1555
100 μg  
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      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MFCAHmAPCMonoclonal Antibody
      Description
      Catalogue NumberMABF1555
      DescriptionAnti-CD80 (mouse), APC, clone 16-10A1 Antibody
      Alternate Names
      • T-lymphocyte activation antigen CD80
      • Activation B7-1 antigen (B7)
      • CD80
      • CD80
      Background InformationThe 16-10A1 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.
      References
      Product Information
      FormatAPC
      PresentationPurified Armenian Hamster monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-CD80 (mouse), APC, clone 16-10A1 Antibody is validated for use in Flow Cytometry for the detection of CD80.
      Key Applications
      • Flow Cytometry
      Biological Information
      ImmunogenImmunogen information for this antibody is proprietary information.
      Clone16-10A1
      ConcentrationPlease refer to lot specific datasheet.
      HostArmenian Hamster
      IsotypeIgG
      Species Reactivity
      • Mouse
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • Cd80
      • B7
      Purification MethodPurified by size-exclusion chromatography
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceThis monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

      Flow Cytometry Analysis: 0.06 μg from a representative lot detected CD80 in one million C57Bl/6 splenocytes.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      MABF1555 04055977293418

      Produits & Applications associés

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      Catégories

      Life Science Research > Antibodies and Assays > Primary Antibodies