Millipore Sigma Vibrant Logo

OP95 Anti-BRCA2 (Ab-1) Mouse mAb (2B)

Aperçu

Tableau de caractéristiques principal

Species ReactivityHostAntibody Type
HMMonoclonal Antibody

Prix & Disponibilité

Référence DisponibilitéConditionnement Qté Prix Quantité
OP95-100UG
Disponibilité limitée
Disponibilité limitée
En stock 
Interrompu(e)
Disponible en quantités limitées
Disponibilité à confirmer
    Pour le restant : Nous vous tiendrons informé
      Pour le restant : Nous vous tiendrons informé
      Nous vous tiendrons informé
      Contacter le Service Clients
      Contact Customer Service

      Flacon en verre 100 μg
      Le prix n'a pas pu être récupéré
      La quantité minimale doit être un multiple de
      Maximum Quantity is
      À la validation de la commande Plus d'informations
      Vous avez sauvegardé ()
       
      Demander le prix
      Description
      OverviewRecognzies the ~460 kDa BRCA2 protein in cells expressing a wild type BRCA2 gene. Sold under license of U.S. Patent 5,753,441 and 6,162,897.
      Catalogue NumberOP95
      Brand Family Calbiochem®
      SynonymsAnti-Breast Cancer Susceptibility Protein
      References
      ReferencesAndres, J.L., et al. 1998. Oncogene 16, 2229.
      Chen, J., et al. 1998. Mol. Cell 2, 317.
      Chen, P.L., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 5287.
      Marmorstein, L.Y., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 13869.
      Connor, F., et al. 1997. Nat. Genet. 17, 423.
      Sharan, S.K., et al. 1997. Nature 386, 804.
      Ludwig, T., et al. 1997. Genes Dev. 11, 1226.
      Mizuta, R., et al. 1997. Proc. Natl. Acad. Sci. USA 94, 6927.
      Rajan, J.V., et al. 1997. Dev. Biol. 184, 385.
      Suzuki, A., et al. 1997. Genes Dev. 11, 1242.
      Wong, A.K.C., et al. 1997. J. Biol. Chem. 272, 31941.
      Cannon-Albright, L.A. and M.H. Skolnick. 1996. Semin. Oncol. 23, 1.
      Goggins, M., et al. 1996. Cancer Res. 56, 5360.
      Stratton, M.R. 1996. Hum. Mol. Genet. 5, 1515.
      Tavtigian, S.V., et al. 1996. Nat. Genet. 12, 333.
      Rajan, J.V., et al. 1996. Proc. Natl. Acad. Sci. USA 93, 13078.
      Spillman, M.A. and A.M. Bowcock. 1996. Oncogene 13, 1639.
      Vaughn, J.P., et al. 1996. Cancer Res. 56, 4590.
      Wooster, R., et al. 1995. Nature 378, 789.
      Product Information
      DeclarationSold under license of U.S. Patents 5,837,492 and 6,124,104.
      FormLiquid
      FormulationIn PBS.
      Positive controlMCF7 cells
      Preservative≤0.1% sodium azide
      Quality LevelMQ100
      Applications
      Key Applications Immunoblotting (Western Blotting)
      Immunoprecipitation
      Application NotesImmunoblotting (2 µg/ml)
      Immunoprecipitation (2 µg)
      Application CommentsThe CAPAN-1 cell line, which has 6174delT mutation in the single BRCA2 allele, expresses a truncated BRCA2 protein of 230 kDa that contains the Anti-BRCA2 epitope and retains RAD51 binding but has lost p53 binding. Full length BRCA2 protein will co-migrate on SDS-PAGE with the catalytic subunit of DNA PK which can be detected using Anti-DNA PK, Cat. No. PC127. Antibody should be titrated for optimal results in individual systems.
      Biological Information
      Immunogena recombinant protein consisting of amino acids 1651-1821 of human BRCA2 fused to GST
      ImmunogenHuman
      Clone2B
      HostMouse
      IsotypeIgG2b
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Concentration Label Please refer to vial label for lot-specific concentration
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Global Trade Item Number
      Référence GTIN
      OP95-100UG 04055977209709