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324355 n-Dodecyl-β-D-maltoside, ULTROL® Grade - CAS 69227-93-6 - Calbiochem

CAS 69227-93-6 is a non-ionic detergent similar to n-octyl-β-D-glucopyranoside; however, increased alkyl chain length has been shown to increase thermal stability of lipid-free rhodopsin in solution.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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324355
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Overview

Replacement Information

Key Spec Table

CAS #
69227-93-6

Pricing & Availability

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324355-100GM
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          324355-250GM
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              324355-25GM
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                  324355-5GM
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                      Description
                      OverviewNon-ionic detergent similar to n-octyl-β-D-glucopyranoside; however, increased alkyl chain length has been shown to increase thermal stability of lipid-free rhodopsin in solution. Useful in membrane-protein solubilization studies. Aggregation number: 98.
                      Absorbance (10%, H2O, 260 nm): <1.0.
                      Catalogue Number324355
                      Brand Family Calbiochem®
                      References
                      ReferencesWitzmann, F., et al. 1991. Electrophoresis 12, 687.
                      Bass, W.T., and Bricker, T.M. 1988. Anal. Biochem. 171, 330.
                      Rosevear, P., et al. 1980. Biochemistry 19, 4108.
                      Grip, W.J., and Bovee-Geurts, P.H.M. 1979. Chem. Phys. Lipids 23, 321.
                      Stubbs, G.W., et al. 1976. Biochim. Biophys. Acta 425, 46.
                      Product Information
                      CAS number69227-93-6
                      Aggregation Number98
                      CMC100-600 µM
                      FormWhite solid
                      Hygroscopic Hygroscopic
                      Micellar weight50000
                      Structure formula ImageStructure formula Image
                      Quality LevelMQ100
                      Applications
                      Biological Information
                      Purity≥98% by HPLC
                      Physicochemical Information
                      Contaminantsdodecanol 1H NMR: ≤1%
                      Dimensions
                      Materials Information
                      Toxicological Information
                      Safety Information according to GHS
                      Safety Information
                      Product Usage Statements
                      Storage and Shipping Information
                      Ship Code Ambient Temperature Only
                      Toxicity Standard Handling
                      Storage +2°C to +8°C
                      Hygroscopic Hygroscopic
                      Do not freeze Ok to freeze
                      Special InstructionsFollowing reconstitution, refrigerate (4°C).
                      Stock solutions are stable for up to 3 months at 4°C.
                      Packaging Information
                      Transport Information
                      Supplemental Information
                      Specifications
                      Global Trade Item Number
                      Catalogue Number GTIN
                      324355-100GM 04055977216417
                      324355-1GM 07790788054175
                      324355-250GM 04055977216431
                      324355-25GM 04055977216424
                      324355-5GM 04055977216448

                      Documentation

                      n-Dodecyl-β-D-maltoside, ULTROL® Grade - CAS 69227-93-6 - Calbiochem SDS

                      Title

                      Safety Data Sheet (SDS) 

                      n-Dodecyl-β-D-maltoside, ULTROL® Grade - CAS 69227-93-6 - Calbiochem Certificates of Analysis

                      TitleLot Number
                      324355

                      References

                      Reference overview
                      Witzmann, F., et al. 1991. Electrophoresis 12, 687.
                      Bass, W.T., and Bricker, T.M. 1988. Anal. Biochem. 171, 330.
                      Rosevear, P., et al. 1980. Biochemistry 19, 4108.
                      Grip, W.J., and Bovee-Geurts, P.H.M. 1979. Chem. Phys. Lipids 23, 321.
                      Stubbs, G.W., et al. 1976. Biochim. Biophys. Acta 425, 46.

                      Brochure

                      Title
                      Biological Detergents Brochure
                      CALBIOSORBﾙ Technical Bulletin

                      Citations

                      Title
                    • Serban P. Georgescu, et al. (2005) Modulator recognition factor 1 (MRF1), an ARID-family member, is a novel co-repressor for estrogen receptor α. Molecular Endocrinology 19, 2491-2501.
                      		•
                      Data Sheet

                      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

                      Revision20-December-2010 JSW
                      DescriptionA water-soluble nonionic detergent. Studies on rhodopsin have shown that alkyl glycosides with longer alkyl chains are better at preserving the protein's properties. In addition, dodecyl maltoside's longer hydrophilic group confers higher solubility in water. This is in contrast to undecyl and dodecyl glucosides, which have low solubility in water. Due to its low CMC, dodecyl maltoside is not easily removed by dialysis. The half time for dialysis is 20 h. This detergent is milder than nonyl glucoside. Of several glycosides tested, dodecyl maltoside was found to be the most useful for the preparation of active cytochrome oxidase from Neurospora. In octyl glucoside, cytochrome oxidase dissociated into its subunits and became inactive. Similarly, beef heart oxidase when equilibrated in octyl glucoside formed a mixture of polymer, dimer, and lower molecular weight forms and underwent denaturation. In contrast, the enzyme, when equilibrated in dodecyl maltoside, was found to exist as a uniform species of 30 kDa, which is consistent with an active dimeric form. Dodecyl maltoside has a critical micelle concentration (CMC) of 100-600 µM and a micellar weight of 70,000. Aggregation number: 98.
                      FormWhite solid
                      CAS number69227-93-6
                      Structure formulaStructure formula
                      Purity≥98% by HPLC
                      Contaminantsdodecanol 1H NMR: ≤1%
                      SolubilityH₂O (100 mg/ml)
                      Storage +2°C to +8°C
                      Hygroscopic
                      Do Not Freeze Ok to freeze
                      Special InstructionsFollowing reconstitution, refrigerate (4°C).
                      Stock solutions are stable for up to 3 months at 4°C.
                      Toxicity Standard Handling
                      ReferencesWitzmann, F., et al. 1991. Electrophoresis 12, 687.
                      Bass, W.T., and Bricker, T.M. 1988. Anal. Biochem. 171, 330.
                      Rosevear, P., et al. 1980. Biochemistry 19, 4108.
                      Grip, W.J., and Bovee-Geurts, P.H.M. 1979. Chem. Phys. Lipids 23, 321.
                      Stubbs, G.W., et al. 1976. Biochim. Biophys. Acta 425, 46.
                      Citation
                    • Serban P. Georgescu, et al. (2005) Modulator recognition factor 1 (MRF1), an ARID-family member, is a novel co-repressor for estrogen receptor α. Molecular Endocrinology 19, 2491-2501.
                      		•