Millipore Sigma Vibrant Logo

05-23-2101 Vasoactive Intestinal Peptide, Human, Porcine, and Rat - CAS 40077-57-4 - Calbiochem

Acts as a mitogenic factor for embryonic neurons in the sympathetic nervous system.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: VIP

Primary Target: Mitogenic factor for embryonic neurons
View Products on Sigmaaldrich.com
05-23-2101
View Pricing & Availability

Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
40077-57-4C₁₄₇H₂₃₈N₄₄O₄₂S

Pricing & Availability

Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
05-23-2101-0.5MG
Retrieving availability...
—
Fulfillment and Delivery Delayed Fulfillment and Delivery Delayed
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      		 Plastic ampoule .5 mg
      Retrieving price...
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
       
      —
      Request Pricing
      		 —
      05-23-2101-1MG
      Retrieving availability...
      —
      Fulfillment and Delivery Delayed Fulfillment and Delivery Delayed
      In Stock 
      Discontinued
      Limited Quantities Available
      Availability to be confirmed
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          		 Glass bottle 1 mg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity is a multiple of
          Maximum Quantity is
          Upon Order Completion More Information
          You Saved ()
           
          —
          Request Pricing
          		 —
          Description
          OverviewActs as a mitogenic factor for embryonic neurons in the sympathetic nervous system. Has powerful hypotensive and vasodilatory effects. Behaves either as a circulating hormone or as a neurotransmitter. Stimulates cAMP production in rat peritoneal macrophages. Inhibits the growth of human small-cell lung carcinoma (SCLC) both in vitro and in vivo, suggesting that it may be useful as a less toxic alternative to conventional chemotherapeutic agents in the treatment of SCLC. Nitric oxide stimulates the release of this peptide.
          Catalogue Number05-23-2101
          Brand Family Calbiochem®
          SynonymsVIP
          References
          ReferencesMaruno, K., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 14373.
          Bakker, R., et al. 1993. Am. J. Physiol. 264, R362.
          Grider, J.R. 1993. Am. J. Physiol. 264, G334.
          Product Information
          CAS number40077-57-4
          ATP CompetitiveN
          FormWhite to off-white lyophilized solid
          FormulationSupplied as a trifluoroacetate salt.
          Hill FormulaC₁₄₇H₂₃₈N₄₄O₄₂S
          Chemical formulaC₁₄₇H₂₃₈N₄₄O₄₂S
          Hygroscopic Hygroscopic
          ReversibleN
          Sold on the basis of peptide contentY
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetMitogenic factor for embryonic neurons
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableN
          Peptide ContentY
          Peptide SequenceH-His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH₂
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 20/21/22

          Harmful by inhalation, in contact with skin and if swallowed.
          S PhraseS: 36

          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Harmful
          Storage -20°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Catalogue Number GTIN
          05-23-2101-0.5MG 04055977226638
          05-23-2101-1MG 04055977226645

          Documentation

          Vasoactive Intestinal Peptide, Human, Porcine, and Rat - CAS 40077-57-4 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          Vasoactive Intestinal Peptide, Human, Porcine, and Rat - CAS 40077-57-4 - Calbiochem Certificates of Analysis

          TitleLot Number
          05-23-2101

          References

          Reference overview
          Maruno, K., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 14373.
          Bakker, R., et al. 1993. Am. J. Physiol. 264, R362.
          Grider, J.R. 1993. Am. J. Physiol. 264, G334.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision18-September-2008 RFH
          SynonymsVIP
          DescriptionActs as a mitogenic factor for embryonic neurons in the sympathetic nervous system. Has powerful hypotensive and vasodilatory effects. Behaves either as a circulating hormone or as a neurotransmitter. Stimulates cAMP production in rat peritoneal macrophages. Nitric oxide stimulates the release of this peptide. Inhibits human small-cell lung carcinoma (SCLC) in nude mice both in vitro and in vivo, suggesting that it may be useful as a less toxic alternative to conventional chemotherapeutic agents in the treatment of SCLC.
          FormWhite to off-white lyophilized solid
          FormulationSupplied as a trifluoroacetate salt.
          CAS number40077-57-4
          Chemical formulaC₁₄₇H₂₃₈N₄₄O₄₂S
          Peptide SequenceH-His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH₂
          Purity≥95% by HPLC
          Solubility5% Acetic acid (1 mg/ml)
          Storage -20°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Harmful
          ReferencesMaruno, K., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 14373.
          Bakker, R., et al. 1993. Am. J. Physiol. 264, R362.
          Grider, J.R. 1993. Am. J. Physiol. 264, G334.