Millipore Sigma Vibrant Logo

605195 Thrombin, Human Plasma, High Activity

Thrombin, Human Plasma, High Activity MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
View Products on Sigmaaldrich.com
605195
View Pricing & Availability

Overview

Replacement Information

Pricing & Availability

Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
605195-1000U
Retrieving availability...
—
Fulfillment and Delivery Delayed Fulfillment and Delivery Delayed
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      		 Plastic ampoule 1000 u
      Retrieving price...
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
       
      —
      Request Pricing
      		 —
      605195-100U
      Retrieving availability...
      —
      Fulfillment and Delivery Delayed Fulfillment and Delivery Delayed
      In Stock 
      Discontinued
      Limited Quantities Available
      Availability to be confirmed
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          		 Glass bottle 100 u
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity is a multiple of
          Maximum Quantity is
          Upon Order Completion More Information
          You Saved ()
           
          —
          Request Pricing
          		 —
          605195-5000U
          Retrieving availability...
          —
          Fulfillment and Delivery Delayed Fulfillment and Delivery Delayed
          In Stock 
          Discontinued
          Limited Quantities Available
          Availability to be confirmed
            Remaining : Will advise
              Remaining : Will advise
              Will advise
              Contact Customer Service
              Contact Customer Service

              		 Plastic ampoule 5000 u
              Retrieving price...
              Price could not be retrieved
              Minimum Quantity is a multiple of
              Maximum Quantity is
              Upon Order Completion More Information
              You Saved ()
               
              —
              Request Pricing
              		 —
              Description
              OverviewDesigned for use in thrombin clotting time tests. Key enzyme that activates factor XIII and converts fibrinogen into fibrin.
              Catalogue Number605195
              Brand Family Calbiochem®
              References
              ReferencesForsberg, G., et al. 1992. J. Protein Chem. 11, 201.
              Garcia, J.G. 1992. J. Lab. Clin. Med. 120, 513.
              Scarborough, R.M., et al. 1992. J. Biol. Chem. 267, 13146.
              Weigel, L.M., et al. 1992. Infect. Immun. 60, 1568.
              Product Information
              CAS number9002-04-4
              Unit of DefinitionOne unit is determined by comparison with a standard curve prepared using the Bureau of Biologics standard thrombin.
              FormLyophilized solid
              FormulationLyophilized from 200 mM NaCl, 50 mM sodium citrate, 0.1% PEG-8000, pH 6.5.
              Quality LevelMQ100
              Applications
              Biological Information
              PurityComplete activation from homogeneous prothrombin by SDS-PAGE
              SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
              Specific Activity≥2800 NIH units/mg protein
              Physicochemical Information
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              RTECSXO8950000
              Safety Information
              R PhraseR: 20/21/22

              Harmful by inhalation, in contact with skin and if swallowed.
              S PhraseS: 36

              Wear suitable protective clothing.
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Blue Ice Only
              Toxicity Harmful
              Storage -20°C
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications
              Global Trade Item Number
              Catalogue Number GTIN
              605195-1000U 04055977188417
              605195-100U 04055977188400
              605195-5000U 04055977188424

              Documentation

              Thrombin, Human Plasma, High Activity SDS

              Title

              Safety Data Sheet (SDS) 

              Thrombin, Human Plasma, High Activity Certificates of Analysis

              TitleLot Number
              605195

              References

              Reference overview
              Forsberg, G., et al. 1992. J. Protein Chem. 11, 201.
              Garcia, J.G. 1992. J. Lab. Clin. Med. 120, 513.
              Scarborough, R.M., et al. 1992. J. Biol. Chem. 267, 13146.
              Weigel, L.M., et al. 1992. Infect. Immun. 60, 1568.
              Data Sheet

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision19-May-2008 RFH
              DescriptionDesigned for use in thrombin clotting time tests. Serine protease formed in the plasma during the clotting process from prothrombin, calcium, and thromboplasmin. Acts on the soluble plasma protein fibrinogen to convert it to an insoluble fibrin clot. Prepared from homogenous human prothrombin by activation with Factor Xa, Factor Va, and phospholipid. Designed for use in thrombin time tests.
              FormLyophilized solid
              FormulationLyophilized from 200 mM NaCl, 50 mM sodium citrate, 0.1% PEG-8000, pH 6.5.
              SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
              CAS number9002-04-4
              RTECSXO8950000
              PurityComplete activation from homogeneous prothrombin by SDS-PAGE
              Specific activity≥2800 NIH units/mg protein
              Unit definitionOne unit is determined by comparison with a standard curve prepared using the Bureau of Biologics standard thrombin.
              SolubilityH₂O (1 mg/ml). Solution will have a cloudy appearance.
              Storage -20°C
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
              Toxicity Harmful
              Merck USA index14, 9383
              ReferencesForsberg, G., et al. 1992. J. Protein Chem. 11, 201.
              Garcia, J.G. 1992. J. Lab. Clin. Med. 120, 513.
              Scarborough, R.M., et al. 1992. J. Biol. Chem. 267, 13146.
              Weigel, L.M., et al. 1992. Infect. Immun. 60, 1568.

              Related Products & Applications

              Alternative Products

              Catalogue Number Description  
              605190 Thrombin, Human Plasma Show Pricing & Availability
              605206 Thrombin, Citrate-Free, Human Plasma Show Pricing & Availability

              Categories

              Life Science Research > Proteins and Enzymes > Other Enzymes