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584110 Tetrahydrobiopterin, Dihydrochloride

Tetrahydrobiopterin, Dihydrochloride MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: THB, 2HCl, (6R)-5,6,7,8-Tetrahydro-L-biopterin•2HCI

584110
  
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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      69056-38-8C₉H₁₅N₅O₃ · 2HCl
      Description
      Overview

      This product has been discontinued.





      A cofactor of inducible nitric oxide synthase. Neuronal nitric oxide synthase has a highly specific site for tetrahydrobiopterin binding.
      Catalogue Number584110
      Brand Family Calbiochem®
      SynonymsTHB, 2HCl, (6R)-5,6,7,8-Tetrahydro-L-biopterin•2HCI
      References
      ReferencesKlatt, P., et al. 1994. J. Biol. Chem. 269, 13861.
      Hirayama, K., et al. 1993. J. Neurochem. 61, 1006.
      Kim, Y.M. and Lancaster, J.R. 1993. FEBS Lett. 332, 255.
      Kwon, N., et al. 1989. J. Biol. Chem. 264, 20496.
      Product Information
      CAS number69056-38-8
      FormWhite solid
      Hill FormulaC₉H₁₅N₅O₃ · 2HCl
      Chemical formulaC₉H₁₅N₅O₃ · 2HCl
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSUO3516500
      Safety Information
      R PhraseR: 20/21/22-36/37/38-40

      Harmful by inhalation, in contact with skin and if swallowed.
      Irritating to eyes, respiratory system and skin.
      Limited evidence of a carcinogenic effect.
      S PhraseS: 22-26-36

      Do not breathe dust.
      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful & Carcinogenic / Teratogenic
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsUnstable in solution; reconstitute just prior to use. Following reconstitution, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      584110 0

      Documentation

      Tetrahydrobiopterin, Dihydrochloride Certificates of Analysis

      TitleLot Number
      584110

      References

      Reference overview
      Klatt, P., et al. 1994. J. Biol. Chem. 269, 13861.
      Hirayama, K., et al. 1993. J. Neurochem. 61, 1006.
      Kim, Y.M. and Lancaster, J.R. 1993. FEBS Lett. 332, 255.
      Kwon, N., et al. 1989. J. Biol. Chem. 264, 20496.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-September-2008 RFH
      SynonymsTHB, 2HCl, (6R)-5,6,7,8-Tetrahydro-L-biopterin•2HCI
      DescriptionA cofactor of inducible nitric oxide synthase. Neuronal nitric oxide synthase has a high specific site for tetrahydrobiopterin binding.
      FormWhite solid
      CAS number69056-38-8
      RTECSUO3516500
      Chemical formulaC₉H₁₅N₅O₃ · 2HCl
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityH₂O (25 mg/ml)
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsUnstable in solution; reconstitute just prior to use. Following reconstitution, aliquot and freeze (-20°C).
      Toxicity Harmful & Carcinogenic / Teratogenic
      ReferencesKlatt, P., et al. 1994. J. Biol. Chem. 269, 13861.
      Hirayama, K., et al. 1993. J. Neurochem. 61, 1006.
      Kim, Y.M. and Lancaster, J.R. 1993. FEBS Lett. 332, 255.
      Kwon, N., et al. 1989. J. Biol. Chem. 264, 20496.