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14-632M TSSK2 Protein, active, 250 µg

14-632M
250 µg  Also available in 10 μg size (cat#14-632) and in bulk (cat#14-632-K).
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      Overview

      Replacement Information
      Description
      Catalogue Number14-632M
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionTSSK2 Protein, active, 250 µg
      OverviewN-terminal His6-tagged, recombinant, full length, human TSSK2, expressed by baculovirus in Sf21 insect cells
      References
      Product Information
      Quality LevelMQ300
      Applications
      ApplicationActive, N-terminal His6-tagged, recombinant, full length, human TSSK2, expressed by baculovirus in Sf21 insect cells, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      Sourcefull length, human TSSK2
      Entrez Gene Number
      Entrez Gene SummaryTSSK2 belongs to a family of serine/threonine kinases highly expressed in testis (Hao et al., 2004 [PubMed 15044604]).[supplied by OMIM]
      Gene Symbol
      • TSSK2
      • FLJ38613
      • DGSG
      • SPOGA2
      • TSK-2
      • STK22B
      • DGS-G
      Protein TargetTSSK2
      Purification MethodNi2+/NTA-agarose
      Target Sub-FamilyCAMK
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q96PF2 # Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm (By similarity).
      COFACTOR: Magnesium (By similarity).
      SIZE: 358 amino acids; 40939 Da
      SUBUNIT: Binds to STK22A (By similarity).
      SUBCELLULAR LOCATION: Cytoplasm (By similarity).
      TISSUE SPECIFICITY: Testis.
      PTM: Autophosphorylated (By similarity).
      DISEASE: SwissProt: Q96PF2 # May play a part in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies. Most cases result from a deletion of chromosome 22q11.2 (the DiGeorge syndrome chromosome region, or DGCR).
      SIMILARITY: SwissProt: Q96PF2 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.
      Molecular Weight44.8kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by phosphorylation of CHKtide
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10 μg size (cat#14-632) and in bulk (cat#14-632-K).
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      14-632M 04053252924453

      Documentation

      Related Products & Applications

      Alternative Packsize

      Catalogue Number Description  
      14-632 TSSK2 Protein, active, 10 µg Show Pricing & Availability

      Product Families

      Categories

      Life Science Research > Proteins and Enzymes > Purified Kinases
      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases