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567703 Spermine NONOate - CAS 136587-13-8 - Calbiochem

Complex of nitric oxide (NO) with spermine.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: N-(2-Aminoethyl)-N-(2-hydroxy-2-nitrosohydrazino)-1,2-ethylenediamine, NOC-22

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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      136587-13-8C₁₀H₂₆N₆O₂
      Description
      OverviewComplex of nitric oxide (NO) with spermine. Convenient reagent for preparing aqueous solutions of NO. Half-life (t½)in PBS, pH 7.4 is 230 minutes at 22°C. Relatively stable in alkaline solution (≥pH 10.0).
      Catalogue Number567703
      Brand Family Calbiochem®
      SynonymsN-(2-Aminoethyl)-N-(2-hydroxy-2-nitrosohydrazino)-1,2-ethylenediamine, NOC-22
      References
      ReferencesRamamurthi, A. and Lewis, R.S. 1997. Chem. Res. Toxicol. 10, 408.
      Hrabie, J.A., et al. 1993. J. Org. Chem. 58, 1472.
      Maragos, C.M., et al. 1993. Cancer Res. 53, 564.
      Wink, D.A., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 9813.
      Maragos, C.M., et al. 1991. J. Med. Chem. 34, 3242.
      Product Information
      CAS number136587-13-8
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₁₀H₂₆N₆O₂
      Chemical formulaC₁₀H₂₆N₆O₂
      Hygroscopic Hygroscopic
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetConvenient reagent for preparing aqueous solutions of NO
      Purity≥98% by UV
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution in alkaline solution, aliquot and freeze (-20°C). Unstable in aqueous solutions; reconstitute in H₂O just prior to use. Alkaline stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      567703 0

      Documentation

      Spermine NONOate - CAS 136587-13-8 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Spermine NONOate - CAS 136587-13-8 - Calbiochem Certificates of Analysis

      TitleLot Number
      567703

      References

      Reference overview
      Ramamurthi, A. and Lewis, R.S. 1997. Chem. Res. Toxicol. 10, 408.
      Hrabie, J.A., et al. 1993. J. Org. Chem. 58, 1472.
      Maragos, C.M., et al. 1993. Cancer Res. 53, 564.
      Wink, D.A., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 9813.
      Maragos, C.M., et al. 1991. J. Med. Chem. 34, 3242.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision11-September-2008 RFH
      SynonymsN-(2-Aminoethyl)-N-(2-hydroxy-2-nitrosohydrazino)-1,2-ethylenediamine, NOC-22
      DescriptionComplex of nitric oxide (NO) with spermine. Convenient reagent for preparing aqueous solutions of NO. Half-life (t½) of NO release = 230 min (PBS, pH 7.4, 22°C).
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number136587-13-8
      Chemical formulaC₁₀H₂₆N₆O₂
      Structure formulaStructure formula
      Purity≥98% by UV
      SolubilityH₂O or 0.1 N NaOH (≥pH 10)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution in alkaline solution, aliquot and freeze (-20°C). Unstable in aqueous solutions; reconstitute in H₂O just prior to use. Alkaline stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesRamamurthi, A. and Lewis, R.S. 1997. Chem. Res. Toxicol. 10, 408.
      Hrabie, J.A., et al. 1993. J. Org. Chem. 58, 1472.
      Maragos, C.M., et al. 1993. Cancer Res. 53, 564.
      Wink, D.A., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 9813.
      Maragos, C.M., et al. 1991. J. Med. Chem. 34, 3242.