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504120 Reboxetine Mesylate - CAS 71620-89-8 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (2R*)-2-[(R*)-(2-Ethoxyphenoxy)phenylmethyl]morpholine methanesulfonate, Edronax, Vestra

Primary Target: Noradrenalin transporter
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504120
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
98769-84-7C₁₉H₂₃NO₃•CH₃SO₃H

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      Description
      OverviewA potent and selective inhibitor of noradrenalin uptake (Ki values are 1.1, 129 and >10000 nM for rat NET, SERT and DAT, respectively). Displays >1000-fold selectivity over α-adrenoceptors, 5-HT, dopamine and muscarinic ACh receptors. Orally active antidepressant.
      Catalogue Number504120
      Brand Family Calbiochem®
      Synonyms(2R*)-2-[(R*)-(2-Ethoxyphenoxy)phenylmethyl]morpholine methanesulfonate, Edronax, Vestra
      References
      ReferencesSacchetti, G., et al. 1999. Br. J. Pharmacol. 128, 1332.
      Wong, E., et al. 2000. Biol. Psychiatry. 47, 818.
      Millan, M., et al. 2001. J. Pharmacol. Exp. Ther. 298,565.
      Owen, J., et al. 2003 Neurosci. Lett. 348, 171.
      Product Information
      CAS number98769-84-7
      FormWhite solid
      Hill FormulaC₁₉H₂₃NO₃•CH₃SO₃H
      Chemical formulaC₁₉H₂₃NO₃•CH₃SO₃H
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetNoradrenalin transporter
      Primary Target K<sub>i</sub>1.1, 129 and > 10000 nM for rat NET, SERT and DAT respectively
      Purity≥99% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze 9-20°C. Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      5.04120.0001 04055977264289

      Documentation

      Reboxetine Mesylate - CAS 71620-89-8 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Reboxetine Mesylate - CAS 71620-89-8 - Calbiochem Certificates of Analysis

      TitleLot Number
      504120

      References

      Reference overview
      Sacchetti, G., et al. 1999. Br. J. Pharmacol. 128, 1332.
      Wong, E., et al. 2000. Biol. Psychiatry. 47, 818.
      Millan, M., et al. 2001. J. Pharmacol. Exp. Ther. 298,565.
      Owen, J., et al. 2003 Neurosci. Lett. 348, 171.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision27-August-2018 JSW
      Synonyms(2R*)-2-[(R*)-(2-Ethoxyphenoxy)phenylmethyl]morpholine methanesulfonate, Edronax, Vestra
      DescriptionA potent and selective inhibitor of noradrenalin uptake (Ki values are 1.1, 129 and >10000 nM for rat NET, SERT and DAT, respectively). Displays >1000-fold selectivity over α-adrenoceptors, 5-HT, dopamine and muscarinic ACh receptors. Orally active antidepressant.
      FormWhite solid
      CAS number98769-84-7
      Chemical formulaC₁₉H₂₃NO₃•CH₃SO₃H
      Structure formulaStructure formula
      Purity≥99% by HPLC
      SolubilityH₂O (20 mg/ml)
      Storage Protect from light
      Avoid freeze/thaw
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze 9-20°C. Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesSacchetti, G., et al. 1999. Br. J. Pharmacol. 128, 1332.
      Wong, E., et al. 2000. Biol. Psychiatry. 47, 818.
      Millan, M., et al. 2001. J. Pharmacol. Exp. Ther. 298,565.
      Owen, J., et al. 2003 Neurosci. Lett. 348, 171.