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480030 NEMO-Binding Domain Binding Peptide, Cell-Permeable, Negative Control - Calbiochem

Overview

Key Spec Table

Empirical Formula
C₁₅₄H₂₄₉N₄₇O₄₂S

Pricing & Availability

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480030-500UG
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      Description
      OverviewA cell-permeable Antennapedia-NBD mutated (Trp739 and Trp741 replaced with Ala) fusion peptide analog of NEMO-Binding Domain Binding Peptide (Cat. No. 480025) that serves as a negative control. Shown to be defective in binding to NEMO. Does not affect the TNF-α-induced phosphorylation of c-Jun and DNA binding of the transcription factor Oct-1.
      Catalogue Number480030
      Brand Family Calbiochem®
      SynonymsDRQIKIWFQNRRMKWKK-TALDASALQTE, NBD-Binding Peptide, Cell-Permeable, Negative Control
      References
      ReferencesJimi, E., et al. 2004. Nat. Med., 10, 617.
      May, M.J., et al. 2000. Science 289, 1550.
      Product Information
      ATP CompetitiveN
      FormLyophilized off-white solid
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₁₅₄H₂₄₉N₄₇O₄₂S
      Chemical formulaC₁₅₄H₂₄₉N₄₇O₄₂S
      Hygroscopic Hygroscopic
      ReversibleN
      Quality LevelMQ100
      Biological Information
      Primary TargetNegative control defective in binding to NEMO
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Peptide SequenceH₂N-Asp-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Thr-Ala-Leu-Asp-Ala-Ser-Ala-Leu-Gln-Thr-Glu-OH
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      480030-500UG 04055977201857