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MAB8705-KC Mouse Anti-Dengue Complex, clone D3-2H2-9-21 (10mg) KC

MAB8705-KC
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      Overview

      Replacement Information
      Description
      Catalogue NumberMAB8705-KC
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionMouse Anti-Dengue Complex, clone D3-2H2-9-21 (10mg) KC
      OverviewThis product is intended for use by IVD manufacturers.
      Contact customer service for assistance: oem.reagents@emdmillipore.com
      Alternate Names
      • Anti-Dengue Complex
      Background InformationDengue fever is an acute, mosquito-transmitted viral disease characterized by fever, headache, arthralgia (severe retro-orbital pain), myalgia, rash, nausea, and vomiting. Infections are caused by any of the four closely related, but antigenically distinct virus serotypes (DEN-1, DEN-2, DEN-3, and DEN-4). Infection with one of these serotypes does not provide cross-protective immunity, so persons living in a dengue-endemic area can have four dengue infections during their lifetimes. Dengue is primarily an urban disease of the tropics, and the viruses that cause it are maintained in a cycle that involves humans and Aedes aegypti, a domestic, day-biting mosquito that prefers to feed on humans. Although most dengue infections result in relatively mild illness, some can produce Dengue Hemorrhagic Fever (DHF) or dengue shock syndrome, with children being particularly at risk. Although epidemic outbreaks have been reported since 1779, the incidence has been increasing, with global, multiple serotype pandemics intensifying within the last 15 years. There is no specific antiviral therapy for dengue, but for both classical dengue and dengue hemorrhagic fever, symptomatic and supportive measures are effective. Important risk factors for DHF include the strain and serotype of the virus involved, as well as the age, immune status, and genetic predisposition of the patient.
      References
      Product Information
      FormatPurified
      Control
      • Dengue positive patient sample
      PresentationProtein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with 0.1% sodium azide as a preservative.
      Quality LevelMQ300
      Applications
      ApplicationDetect Dengue Virus Complex using this Anti-Dengue Virus Complex Antibody, clone D3-2H2-9-21 validated for use in IC & IF.
      Key Applications
      • Immunocytochemistry
      • Immunofluorescence
      Application NotesImmunofluorescence.

      Immunocytochemistry on acetone fixed material.

      Suggested working dilution: 1:50-400.

      Final working dilutions must be determined by end user.
      Biological Information
      ImmunogenDengue type 4 virus antigens.
      CloneD3-2H2-9-21
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityReacts with all members of the Dengue complex.
      IsotypeIgG2a
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Purification MethodProtein A Purfied
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Minimum order quantity required to qualify. Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain for 6 months at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
      Packaging Information
      Material SizeBulk packaging. Please inquire.
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MAB8705-KC 04053252642333

      Related Products & Applications

      Alternative Packsize

      Catalogue Number Description  
      MAB8705 Anti-Dengue Virus Complex Antibody, clone D3-2H2-9-21 Show Pricing & Availability
      MAB8705-K Mouse Anti-Dengue Complex, clone D3-2H2-9-21 (1mg) Show Pricing & Availability

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies
      IVD/OEM Materials & Reagents > Bulk & Custom Antibodies > Primary Bulk Antibodies by Target > Viruses by Family > Flaviviridae
      IVD/OEM Materials & Reagents > Bulk & Custom Antibodies > Primary Bulk Antibodies by Target > Viruses by Clinical Condition > Haemorrhagic
      IVD/OEM Materials & Reagents > Bulk & Custom Antibodies > Primary Bulk Antibodies by Target > Viruses by Clinical Condition > Blood borne Viruses
      IVD/OEM Materials & Reagents > Bulk & Custom Antibodies > Primary Bulk Antibodies by Target > Viruses by Clinical Condition > Vector borne